Ehrhardt JD - Search Results

1

I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going?

Bousquet P, Greney H, Bruban V, Schann S, Ehrhardt JD, Monassier L, Feldman J. Bousquet P, et al. Among authors: ehrhardt jd. Ann N Y Acad Sci. 2003 Dec;1009:228-33. doi: 10.1196/annals.1304.028. Ann N Y Acad Sci. 2003. PMID: 15028592 Review.

2

Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation.

Bruban V, Estato V, Schann S, Ehrhardt JD, Monassier L, Renard P, Scalbert E, Feldman J, Bousquet P. Bruban V, et al. Among authors: ehrhardt jd. Circulation. 2002 Mar 5;105(9):1116-21. doi: 10.1161/hc0802.104328. Circulation. 2002. PMID: 11877365

3

[125I]2-(2-chloro-4-iodo-phenylamino)-5-methyl-pyrroline (LNP 911), a high-affinity radioligand selective for I1 imidazoline receptors.

Greney H, Urosevic D, Schann S, Dupuy L, Bruban V, Ehrhardt JD, Bousquet P, Dontenwill M. Greney H, et al. Among authors: ehrhardt jd. Mol Pharmacol. 2002 Jul;62(1):181-91. doi: 10.1124/mol.62.1.181. Mol Pharmacol. 2002. PMID: 12065769

4

LNP 906, the first high-affinity photoaffinity ligand selective for I1 imidazoline receptors.

Urosevic D, Schann S, Ehrhardt JD, Bousquet P, Greney H. Urosevic D, et al. Among authors: ehrhardt jd. Br J Pharmacol. 2004 Jun;142(3):609-17. doi: 10.1038/sj.bjp.0705784. Br J Pharmacol. 2004. PMID: 15178642 Free PMC article.

5

Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.

Gasparik V, Greney H, Schann S, Feldman J, Fellmann L, Ehrhardt JD, Bousquet P. Gasparik V, et al. Among authors: ehrhardt jd. J Med Chem. 2015 Jan 22;58(2):878-87. doi: 10.1021/jm501456p. Epub 2014 Dec 31. J Med Chem. 2015. PMID: 25521963

6

Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline receptor selective ligand with hypotensive activity.

Schann S, Bruban V, Pompermayer K, Feldman J, Pfeiffer B, Renard P, Scalbert E, Bousquet P, Ehrhardt JD. Schann S, et al. Among authors: ehrhardt jd. J Med Chem. 2001 May 10;44(10):1588-93. doi: 10.1021/jm001111b. J Med Chem. 2001. PMID: 11334568

7

Participation of imidazoline receptors and alpha(2-)-adrenoceptors in the central hypotensive effects of imidazoline-like drugs.

Bousquet P, Bruban V, Schann S, Greney H, Ehrhardt JD, Dontenwill M, Feldman J. Bousquet P, et al. Among authors: ehrhardt jd. Ann N Y Acad Sci. 1999 Jun 21;881:272-8. doi: 10.1111/j.1749-6632.1999.tb09369.x. Ann N Y Acad Sci. 1999. PMID: 10415925 Review.

8

Methylation of imidazoline related compounds leads to loss of α₂-adrenoceptor affinity. Synthesis and biological evaluation of selective I₁ imidazoline receptor ligands.

Schann S, Greney H, Gasparik V, Dontenwill M, Rascente C, Lacroix G, Monassier L, Bruban V, Feldman J, Ehrhardt JD, Bousquet P. Schann S, et al. Among authors: ehrhardt jd. Bioorg Med Chem. 2012 Aug 1;20(15):4710-5. doi: 10.1016/j.bmc.2012.06.008. Epub 2012 Jun 9. Bioorg Med Chem. 2012. PMID: 22750139

9

Structure-affinity relationship of cirazoline derivatives for idazoxan imidazoline-specific sites in the human cerebral cortex and the rabbit kidney.

Brasili L, Pigini M, Ehrhardt JD, Molines A, Greney H, Bousquet P, Dontenwill M. Brasili L, et al. Among authors: ehrhardt jd. Ann N Y Acad Sci. 1995 Jul 12;763:149-52. doi: 10.1111/j.1749-6632.1995.tb32399.x. Ann N Y Acad Sci. 1995. PMID: 7677323 No abstract available.

10

Binding of new cirazoline derivative to imidazoline receptors from human brain.

Dontenwill M, Ehrhardt JD, Senecheau P, Molines A, Greney H, Bousquet P. Dontenwill M, et al. Among authors: ehrhardt jd. Neurochem Int. 1997 Jan;30(1):9-16. doi: 10.1016/s0197-0186(96)00034-4. Neurochem Int. 1997. PMID: 9116592

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