Joachimiak LA - Search Results

1

Computational redesign of protein-protein interaction specificity.

Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Kortemme T, et al. Among authors: joachimiak la. Nat Struct Mol Biol. 2004 Apr;11(4):371-9. doi: 10.1038/nsmb749. Epub 2004 Mar 21. Nat Struct Mol Biol. 2004. PMID: 15034550

2

Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface.

Joachimiak LA, Kortemme T, Stoddard BL, Baker D. Joachimiak LA, et al. J Mol Biol. 2006 Aug 4;361(1):195-208. doi: 10.1016/j.jmb.2006.05.022. Epub 2006 May 24. J Mol Biol. 2006. PMID: 16831445

3

Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases.

Keeble AH, Joachimiak LA, Maté MJ, Meenan N, Kirkpatrick N, Baker D, Kleanthous C. Keeble AH, et al. Among authors: joachimiak la. J Mol Biol. 2008 Jun 13;379(4):745-59. doi: 10.1016/j.jmb.2008.03.055. Epub 2008 Apr 3. J Mol Biol. 2008. PMID: 18471830

4

A de novo protein binding pair by computational design and directed evolution.

Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. Karanicolas J, et al. Among authors: joachimiak la. Mol Cell. 2011 Apr 22;42(2):250-60. doi: 10.1016/j.molcel.2011.03.010. Epub 2011 Mar 31. Mol Cell. 2011. PMID: 21458342 Free PMC article.

5

Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.

Zhang J, Ma B, DiMaio F, Douglas NR, Joachimiak LA, Baker D, Frydman J, Levitt M, Chiu W. Zhang J, et al. Among authors: joachimiak la. Structure. 2011 May 11;19(5):633-9. doi: 10.1016/j.str.2011.03.005. Structure. 2011. PMID: 21565698 Free PMC article.

6

Conservation of a novel protein associated with an antibiotic efflux operon in Burkholderia cenocepacia.

Nair BM, Joachimiak LA, Chattopadhyay S, Montano I, Burns JL. Nair BM, et al. Among authors: joachimiak la. FEMS Microbiol Lett. 2005 Apr 15;245(2):337-44. doi: 10.1016/j.femsle.2005.03.027. FEMS Microbiol Lett. 2005. PMID: 15837391

7

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.

Tam S, Spiess C, Auyeung W, Joachimiak L, Chen B, Poirier MA, Frydman J. Tam S, et al. Nat Struct Mol Biol. 2009 Dec;16(12):1279-85. doi: 10.1038/nsmb.1700. Epub 2009 Nov 15. Nat Struct Mol Biol. 2009. PMID: 19915590 Free PMC article.

8

Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone.

Ryder BD, Matlahov I, Bali S, Vaquer-Alicea J, van der Wel PCA, Joachimiak LA. Ryder BD, et al. Among authors: joachimiak la. Nat Commun. 2021 Feb 11;12(1):946. doi: 10.1038/s41467-021-21147-x. Nat Commun. 2021. PMID: 33574241 Free PMC article.

9

DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation.

Hou Z, Wydorski PM, Perez VA, Mendoza-Oliva A, Ryder BD, Mirbaha H, Kashmer O, Joachimiak LA. Hou Z, et al. Among authors: joachimiak la. Nat Commun. 2021 Sep 9;12(1):5338. doi: 10.1038/s41467-021-25635-y. Nat Commun. 2021. PMID: 34504072 Free PMC article.

10

The molecular architecture of the eukaryotic chaperonin TRiC/CCT.

Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J. Leitner A, et al. Among authors: joachimiak la. Structure. 2012 May 9;20(5):814-25. doi: 10.1016/j.str.2012.03.007. Epub 2012 Apr 12. Structure. 2012. PMID: 22503819 Free PMC article.

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