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The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner.
Alberich Jordà M, Rayman N, Tas M, Verbakel SE, Battista N, van Lom K, Löwenberg B, Maccarrone M, Delwel R. Alberich Jordà M, et al. Among authors: van lom k. Blood. 2004 Jul 15;104(2):526-34. doi: 10.1182/blood-2003-12-4357. Epub 2004 Mar 23. Blood. 2004. PMID: 15039279 Free article.
Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling.
Taskesen E, Havermans M, van Lom K, Sanders MA, van Norden Y, Bindels E, Hoogenboezem R, Reinders MJ, Figueroa ME, Valk PJ, Löwenberg B, Melnick A, Delwel R. Taskesen E, et al. Among authors: van lom k, van norden y. Blood. 2014 May 22;123(21):3327-35. doi: 10.1182/blood-2013-07-512855. Epub 2014 Mar 25. Blood. 2014. PMID: 24668493 Free article.
An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.
Avellino R, Havermans M, Erpelinck C, Sanders MA, Hoogenboezem R, van de Werken HJ, Rombouts E, van Lom K, van Strien PM, Gebhard C, Rehli M, Pimanda J, Beck D, Erkeland S, Kuiken T, de Looper H, Gröschel S, Touw I, Bindels E, Delwel R. Avellino R, et al. Among authors: van lom k. Blood. 2016 Jun 16;127(24):2991-3003. doi: 10.1182/blood-2016-01-695759. Epub 2016 Mar 10. Blood. 2016. PMID: 26966090 Free PMC article.
60 results