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Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels.
Hu T, Stearns BA, Campbell BT, Arruda JM, Chen C, Aiyar J, Bezverkov RE, Santini A, Schaffhauser H, Liu W, Venkatraman S, Munoz B. Hu T, et al. Among authors: aiyar j. Bioorg Med Chem Lett. 2004 May 3;14(9):2031-4. doi: 10.1016/j.bmcl.2004.02.070. Bioorg Med Chem Lett. 2004. PMID: 15080973
Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the alpha 2 delta-1 subunit of voltage gated calcium channel.
Lebsack AD, Gunzner J, Wang B, Pracitto R, Schaffhauser H, Santini A, Aiyar J, Bezverkov R, Munoz B, Liu W, Venkatraman S. Lebsack AD, et al. Among authors: aiyar j. Bioorg Med Chem Lett. 2004 May 17;14(10):2463-7. doi: 10.1016/j.bmcl.2004.03.008. Bioorg Med Chem Lett. 2004. PMID: 15109633
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels.
Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS; International Union of Pharmacology. Gutman GA, et al. Among authors: aiyar j. Pharmacol Rev. 2003 Dec;55(4):583-6. doi: 10.1124/pr.55.4.9. Pharmacol Rev. 2003. PMID: 14657415
32 results