Koch WJ - Search Results

1

Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts.

Williams ML, Hata JA, Schroder J, Rampersaud E, Petrofski J, Jakoi A, Milano CA, Koch WJ. Williams ML, et al. Among authors: koch wj. Circulation. 2004 Apr 6;109(13):1590-3. doi: 10.1161/01.CIR.0000125521.40985.28. Epub 2004 Mar 29. Circulation. 2004. PMID: 15051637

2

Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1.

Ferguson SS, Ménard L, Barak LS, Koch WJ, Colapietro AM, Caron MG. Ferguson SS, et al. Among authors: koch wj. J Biol Chem. 1995 Oct 20;270(42):24782-9. doi: 10.1074/jbc.270.42.24782. J Biol Chem. 1995. PMID: 7559596 Free article.

3

Mutational analysis of the pleckstrin homology domain of the beta-adrenergic receptor kinase. Differential effects on G beta gamma and phosphatidylinositol 4,5-bisphosphate binding.

Touhara K, Koch WJ, Hawes BE, Lefkowitz RJ. Touhara K, et al. Among authors: koch wj. J Biol Chem. 1995 Jul 14;270(28):17000-5. doi: 10.1074/jbc.270.28.17000. J Biol Chem. 1995. PMID: 7622521 Free article.

4

Cardiac muscarinic potassium channel activity is attenuated by inhibitors of G beta gamma.

Nair LA, Inglese J, Stoffel R, Koch WJ, Lefkowitz RJ, Kwatra MM, Grant AO. Nair LA, et al. Among authors: koch wj. Circ Res. 1995 May;76(5):832-8. doi: 10.1161/01.res.76.5.832. Circ Res. 1995. PMID: 7729000

5

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Koch WJ, et al. Science. 1995 Jun 2;268(5215):1350-3. doi: 10.1126/science.7761854. Science. 1995. PMID: 7761854

6

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.

Koch WJ, Hawes BE, Allen LF, Lefkowitz RJ. Koch WJ, et al. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12706-10. doi: 10.1073/pnas.91.26.12706. Proc Natl Acad Sci U S A. 1994. PMID: 7809106 Free PMC article.

7

Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.

Koch WJ, Hawes BE, Inglese J, Luttrell LM, Lefkowitz RJ. Koch WJ, et al. J Biol Chem. 1994 Feb 25;269(8):6193-7. J Biol Chem. 1994. PMID: 8119963 Free article.

8

Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.

Inglese J, Luttrell LM, Iñiguez-Lluhi JA, Touhara K, Koch WJ, Lefkowitz RJ. Inglese J, et al. Among authors: koch wj. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3637-41. doi: 10.1073/pnas.91.9.3637. Proc Natl Acad Sci U S A. 1994. PMID: 8170960 Free PMC article.

9

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.

Koch WJ, Inglese J, Stone WC, Lefkowitz RJ. Koch WJ, et al. J Biol Chem. 1993 Apr 15;268(11):8256-60. J Biol Chem. 1993. PMID: 8463335 Free article.

10

Transgenic manipulation of myocardial G protein-coupled receptors and receptor kinases.

Koch WJ, Milano CA, Lefkowitz RJ. Koch WJ, et al. Circ Res. 1996 Apr;78(4):511-6. doi: 10.1161/01.res.78.4.511. Circ Res. 1996. PMID: 8635207 Review. No abstract available.

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