Kirkesseli S - Search Results

1

Estimating mass balance for inhaled drugs in humans: an example with a VLA-4 antagonist, IVL745.

Rohatagi S, Shah B, Zhang J, Zeng Z, Kirkesseli S, Jensen BK. Rohatagi S, et al. Among authors: kirkesseli s. J Clin Pharmacol. 2004 Apr;44(4):348-58. doi: 10.1177/0091270004263465. J Clin Pharmacol. 2004. PMID: 15051741 Clinical Trial.

2

Pharmacoscintigraphic comparison of HMR 1031, a VLA-4 antagonist, in healthy volunteers following delivery via a nebulizer and a dry powder inhaler.

Rohatagi S, Chapel S, Kirkesseli S, Newman S, Zhang J, Paccaly D, Randall L, Wray H, Wellington S, Shah B, Jensen BK. Rohatagi S, et al. Among authors: kirkesseli s. Am J Ther. 2004 Mar-Apr;11(2):103-13. doi: 10.1097/00045391-200403000-00005. Am J Ther. 2004. PMID: 14999362 Clinical Trial.

3

Pharmacokinetics, pharmacodynamics, and safety of a lipid-lowering adenosine A1 agonist, RPR749, in healthy subjects.

Shah B, Rohatagi S, Natarajan C, Kirkesseli S, Baybutt R, Jensen BK. Shah B, et al. Among authors: kirkesseli s. Am J Ther. 2004 May-Jun;11(3):175-89. doi: 10.1097/00045391-200405000-00005. Am J Ther. 2004. PMID: 15133532 Clinical Trial.

4

Pharmacokinetics, pharmacodynamics, and safety of inhaled cyclosporin A (ADI628) after single and repeated administration in healthy male and female subjects and asthmatic patients.

Rohatagi S, Calic F, Harding N, Ozoux ML, Bouriot JP, Kirkesseli S, DeLeij L, Jensen BK. Rohatagi S, et al. Among authors: kirkesseli s. J Clin Pharmacol. 2000 Nov;40(11):1211-26. J Clin Pharmacol. 2000. PMID: 11075307 Clinical Trial.

5

Pharmacokinetics, pharmacodynamics, and safety of a platelet GPIIb/IIIa antagonist, RGD891, following intravenous administration in healthy male volunteers.

Zannikos PN, Rohatagi S, Jensen BK, DePhillips SL, Massignon D, Calic F, Sibille M, Kirkesseli S. Zannikos PN, et al. Among authors: kirkesseli s. J Clin Pharmacol. 2000 Nov;40(11):1245-56. J Clin Pharmacol. 2000. PMID: 11075310 Clinical Trial.

6

Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma.

Norris V, Choong L, Tran D, Corden Z, Boyce M, Arshad H, Holgate S, O'Connor B, Millet S, Miller B, Rohatagi S, Kirkesseli S. Norris V, et al. Among authors: kirkesseli s. J Allergy Clin Immunol. 2005 Oct;116(4):761-7. doi: 10.1016/j.jaci.2005.04.045. Epub 2005 Aug 19. J Allergy Clin Immunol. 2005. PMID: 16210048 Clinical Trial.

7

Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity.

Fayer JL, Zannikos PN, Stevens JC, Luo Y, Sidhu R, Kirkesseli S. Fayer JL, et al. Among authors: kirkesseli s. J Clin Pharmacol. 2001 Mar;41(3):305-16. doi: 10.1177/00912700122010122. J Clin Pharmacol. 2001. PMID: 11269571 Clinical Trial.

8

Single- and multiple-dose pharmacokinetics of riluzole in white subjects.

Le Liboux A, Lefebvre P, Le Roux Y, Truffinet P, Aubeneau M, Kirkesseli S, Montay G. Le Liboux A, et al. Among authors: kirkesseli s. J Clin Pharmacol. 1997 Sep;37(9):820-7. doi: 10.1002/j.1552-4604.1997.tb05630.x. J Clin Pharmacol. 1997. PMID: 9549636 Clinical Trial.

9

A comparison of the pharmacokinetics and tolerability of riluzole after repeat dose administration in healthy elderly and young volunteers.

Le Liboux A, Cachia JP, Kirkesseli S, Gautier JY, Guimart C, Montay G, Peeters PA, Groen E, Jonkman JH, Wemer J. Le Liboux A, et al. Among authors: kirkesseli s. J Clin Pharmacol. 1999 May;39(5):480-6. J Clin Pharmacol. 1999. PMID: 10234595

10

First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased sphingosine-1 phosphate receptor-1 agonist for endothelial protection.

Bergougnan L, Armani S, Golor G, Tardat A, Vitse O, Hurbin F, Scemama M, Poitiers F, Radzik D, Gaudin C, Hovsepian L, Muslin AJ, Kirkesseli S, Deutsch P, Parkar AA. Bergougnan L, et al. Among authors: kirkesseli s. Br J Clin Pharmacol. 2021 Feb;87(2):598-611. doi: 10.1111/bcp.14422. Epub 2020 Jul 8. Br J Clin Pharmacol. 2021. PMID: 32520410 Free PMC article. Clinical Trial.

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