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Binding site elucidation of hydantoin-based antagonists of LFA-1 using multidisciplinary technologies: evidence for the allosteric inhibition of a protein--protein interaction.
Last-Barney K, Davidson W, Cardozo M, Frye LL, Grygon CA, Hopkins JL, Jeanfavre DD, Pav S, Qian C, Stevenson JM, Tong L, Zindell R, Kelly TA. Last-Barney K, et al. Among authors: davidson w. J Am Chem Soc. 2001 Jun 20;123(24):5643-50. doi: 10.1021/ja0104249. J Am Chem Soc. 2001. PMID: 11403595
Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.
Ward YD, Thomson DS, Frye LL, Cywin CL, Morwick T, Emmanuel MJ, Zindell R, McNeil D, Bekkali Y, Girardot M, Hrapchak M, DeTuri M, Crane K, White D, Pav S, Wang Y, Hao MH, Grygon CA, Labadia ME, Freeman DM, Davidson W, Hopkins JL, Brown ML, Spero DM. Ward YD, et al. Among authors: davidson w. J Med Chem. 2002 Dec 5;45(25):5471-82. doi: 10.1021/jm020209i. J Med Chem. 2002. PMID: 12459015
Catalysis and function of the p38 alpha.MK2a signaling complex.
Lukas SM, Kroe RR, Wildeson J, Peet GW, Frego L, Davidson W, Ingraham RH, Pargellis CA, Labadia ME, Werneburg BG. Lukas SM, et al. Among authors: davidson w. Biochemistry. 2004 Aug 10;43(31):9950-60. doi: 10.1021/bi049508v. Biochemistry. 2004. PMID: 15287722
The design of potent hydrazones and disulfides as cathepsin S inhibitors.
Cywin CL, Firestone RA, McNeil DW, Grygon CA, Crane KM, White DM, Kinkade PR, Hopkins JL, Davidson W, Labadia ME, Wildeson J, Morelock MM, Peterson JD, Raymond EL, Brown ML, Spero DM. Cywin CL, et al. Among authors: davidson w. Bioorg Med Chem. 2003 Mar 6;11(5):733-40. doi: 10.1016/s0968-0896(02)00468-6. Bioorg Med Chem. 2003. PMID: 12538003
1,019 results