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Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5.
Wang Q, Walsh DM, Rowan MJ, Selkoe DJ, Anwyl R. Wang Q, et al. Among authors: rowan mj. J Neurosci. 2004 Mar 31;24(13):3370-8. doi: 10.1523/JNEUROSCI.1633-03.2004. J Neurosci. 2004. PMID: 15056716 Free PMC article.
204 results