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Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G. Andreozzi F, et al. Among authors: d alessandris c. Endocrinology. 2004 Jun;145(6):2845-57. doi: 10.1210/en.2003-0939. Epub 2004 Mar 4. Endocrinology. 2004. PMID: 15001544
Endocrine and paracrine regulation of cumulus expansion.
Salustri A, Camaioni A, D'Alessandris C. Salustri A, et al. Among authors: d alessandris c. Zygote. 1996 Nov;4(4):313-5. doi: 10.1017/s0967199400003312. Zygote. 1996. PMID: 9153772 Review. No abstract available.