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Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.
Pant V, Kurukuti S, Pugacheva E, Shamsuddin S, Mariano P, Renkawitz R, Klenova E, Lobanenkov V, Ohlsson R. Pant V, et al. Among authors: klenova e. Mol Cell Biol. 2004 Apr;24(8):3497-504. doi: 10.1128/MCB.24.8.3497-3504.2004. Mol Cell Biol. 2004. PMID: 15060168 Free PMC article.
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.
Yu W, Ginjala V, Pant V, Chernukhin I, Whitehead J, Docquier F, Farrar D, Tavoosidana G, Mukhopadhyay R, Kanduri C, Oshimura M, Feinberg AP, Lobanenkov V, Klenova E, Ohlsson R. Yu W, et al. Among authors: klenova e. Nat Genet. 2004 Oct;36(10):1105-10. doi: 10.1038/ng1426. Epub 2004 Sep 7. Nat Genet. 2004. PMID: 15361875
CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide.
Chernukhin I, Shamsuddin S, Kang SY, Bergström R, Kwon YW, Yu W, Whitehead J, Mukhopadhyay R, Docquier F, Farrar D, Morrison I, Vigneron M, Wu SY, Chiang CM, Loukinov D, Lobanenkov V, Ohlsson R, Klenova E. Chernukhin I, et al. Among authors: klenova e. Mol Cell Biol. 2007 Mar;27(5):1631-48. doi: 10.1128/MCB.01993-06. Epub 2007 Jan 8. Mol Cell Biol. 2007. PMID: 17210645 Free PMC article.
65 results