Mertens N - Search Results

1

New strategies in polypeptide and antibody synthesis: an overview.

Mertens N, Devos F, Leoen J, Van Deynse E, Willems A, Schoonooghe S, Burvenich I, De Koker S, Vlieghe D, Grooten J, Kelly A, Van de Wiele C. Mertens N, et al. Cancer Biother Radiopharm. 2004 Feb;19(1):99-109. doi: 10.1089/108497804773391748. Cancer Biother Radiopharm. 2004. PMID: 15068618 Review.

2

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives.

Willems A, Leoen J, Schoonooghe S, Grooten J, Mertens N. Willems A, et al. Among authors: mertens n. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):161-76. doi: 10.1016/s1570-0232(02)00813-9. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12651012

3

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain.

Schoonjans R, Willems A, Schoonooghe S, Leoen J, Grooten J, Mertens N. Schoonjans R, et al. Among authors: mertens n. Biomol Eng. 2001 Jun;17(6):193-202. doi: 10.1016/s1389-0344(01)00066-1. Biomol Eng. 2001. PMID: 11337278

4

Radiolabeled annexin-V for monitoring treatment response in oncology.

Van de Wiele C, Vermeersch H, Loose D, Signore A, Mertens N, Dierckx R. Van de Wiele C, et al. Among authors: mertens n. Cancer Biother Radiopharm. 2004 Apr;19(2):189-94. doi: 10.1089/108497804323071968. Cancer Biother Radiopharm. 2004. PMID: 15186599 Review.

5

CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation.

Willems A, Schoonooghe S, Eeckhout D, De Jaeger G, Grooten J, Mertens N. Willems A, et al. Among authors: mertens n. Cancer Immunol Immunother. 2005 Nov;54(11):1059-71. doi: 10.1007/s00262-005-0671-8. Epub 2005 May 13. Cancer Immunol Immunother. 2005. PMID: 15891885 Free PMC article.

6

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris.

Schoonooghe S, Kaigorodov V, Zawisza M, Dumolyn C, Haustraete J, Grooten J, Mertens N. Schoonooghe S, et al. Among authors: mertens n. BMC Biotechnol. 2009 Aug 11;9:70. doi: 10.1186/1472-6750-9-70. BMC Biotechnol. 2009. PMID: 19671134 Free PMC article.

7

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1.

Schoonooghe S, Burvenich I, Vervoort L, De Vos F, Mertens N, Grooten J. Schoonooghe S, et al. Among authors: mertens n. Protein Eng Des Sel. 2010 Sep;23(9):721-8. doi: 10.1093/protein/gzq044. Epub 2010 Jul 8. Protein Eng Des Sel. 2010. PMID: 20616115

8

Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.

Schoonjans R, Willems A, Schoonooghe S, Fiers W, Grooten J, Mertens N. Schoonjans R, et al. Among authors: mertens n. J Immunol. 2000 Dec 15;165(12):7050-7. doi: 10.4049/jimmunol.165.12.7050. J Immunol. 2000. PMID: 11120833

9

Efficient heterodimerization of recombinant bi- and trispecific antibodies.

Schoonjans R, Willems A, Grooten J, Mertens N. Schoonjans R, et al. Among authors: mertens n. Bioseparation. 2000;9(3):179-83. doi: 10.1023/a:1008120203269. Bioseparation. 2000. PMID: 11105248

10

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

Burvenich I, Schoonooghe S, Cornelissen B, Blanckaert P, Coene E, Cuvelier C, Mertens N, Slegers G. Burvenich I, et al. Among authors: mertens n. Clin Cancer Res. 2005 Oct 15;11(20):7288-96. doi: 10.1158/1078-0432.CCR-04-2503. Clin Cancer Res. 2005. PMID: 16243799

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