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Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.
Gugliucci A, Ranzato L, Scorrano L, Colonna R, Petronilli V, Cusan C, Prato M, Mancini M, Pagano F, Bernardi P. Gugliucci A, et al. Among authors: petronilli v. J Biol Chem. 2002 Aug 30;277(35):31789-95. doi: 10.1074/jbc.M204450200. Epub 2002 Jun 21. J Biol Chem. 2002. PMID: 12080072 Free article.
Treatment with 1 microM MK886 plus indomethacin sensitized cells to killing by exogenous arachidonic acid, which induces PTP opening and cytochrome c release (Scorrano, L., Penzo, D., Petronilli, V., Pagano, F., and Bernardi, P. (2001) J. Biol. Chem. 276, 12035-1204 …
Treatment with 1 microM MK886 plus indomethacin sensitized cells to killing by exogenous arachidonic acid, which induces PTP opening and cyt …
The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.
Milanesi E, Costantini P, Gambalunga A, Colonna R, Petronilli V, Cabrelle A, Semenzato G, Cesura AM, Pinard E, Bernardi P. Milanesi E, et al. Among authors: petronilli v. J Biol Chem. 2006 Apr 14;281(15):10066-72. doi: 10.1074/jbc.M513708200. Epub 2006 Feb 14. J Biol Chem. 2006. PMID: 16481323 Free article.
Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore.
Scorrano L, Petronilli V, Di Lisa F, Bernardi P. Scorrano L, et al. Among authors: petronilli v. J Biol Chem. 1999 Aug 6;274(32):22581-5. doi: 10.1074/jbc.274.32.22581. J Biol Chem. 1999. PMID: 10428836 Free article.
By using a novel in situ assay based on the fluorescence changes of mitochondrially entrapped calcein (Petronilli, V., Miotto, G., Canton, M., Colonna, R., Bernardi, P., and Di Lisa, F. (1999) Biophys. ...
By using a novel in situ assay based on the fluorescence changes of mitochondrially entrapped calcein (Petronilli, V., Miotto, …
The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ.
Petronilli V, Penzo D, Scorrano L, Bernardi P, Di Lisa F. Petronilli V, et al. J Biol Chem. 2001 Apr 13;276(15):12030-4. doi: 10.1074/jbc.M010604200. Epub 2000 Dec 27. J Biol Chem. 2001. PMID: 11134038 Free article.
Treatment with arachidonic acid or induces PTP opening in situ with similar kinetics, as assessed by the calcein loading-Co(2+) quenching technique (Petronilli, V., Miotto, G., Canton, M., Colonna, R., Bernardi, P., and Di Lisa, F. (1999) Biophys. ...
Treatment with arachidonic acid or induces PTP opening in situ with similar kinetics, as assessed by the calcein loading-Co(2+) quenching te …
96 results