Young DV - Search Results

1

Combination of paclitaxel and nitric oxide as a novel treatment for the reduction of restenosis.

Lin CE, Garvey DS, Janero DR, Letts LG, Marek P, Richardson SK, Serebryanik D, Shumway MJ, Tam SW, Trocha AM, Young DV. Lin CE, et al. Among authors: young dv. J Med Chem. 2004 Apr 22;47(9):2276-82. doi: 10.1021/jm0304111. J Med Chem. 2004. PMID: 15084126

2

Synthesis and structure-activity relationship of novel, highly potent metharyl and methcycloalkyl cyclooxygenase-2 (COX-2) selective inhibitors.

Khanapure SP, Garvey DS, Young DV, Ezawa M, Earl RA, Gaston RD, Fang X, Murty M, Martino A, Shumway M, Trocha M, Marek P, Tam SW, Janero DR, Letts LG. Khanapure SP, et al. Among authors: young dv. J Med Chem. 2003 Dec 4;46(25):5484-504. doi: 10.1021/jm030268b. J Med Chem. 2003. PMID: 14640557

3

Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles.

Ranatunge RR, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Young DV, Zemetseva IS. Ranatunge RR, et al. Among authors: young dv. Bioorg Med Chem. 2004 Mar 15;12(6):1357-66. doi: 10.1016/j.bmc.2004.01.012. Bioorg Med Chem. 2004. PMID: 15018908

4

Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.

Ranatunge RR, Augustyniak M, Bandarage UK, Earl RA, Ellis JL, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Schroeder JD, Shumway MJ, Tam SW, Trocha AM, Young DV. Ranatunge RR, et al. Among authors: young dv. J Med Chem. 2004 Apr 22;47(9):2180-93. doi: 10.1021/jm030276s. J Med Chem. 2004. PMID: 15084117

5

3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.

Ranatunge RR, Earl RA, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Schwalb DJ, Young DV, Zemtseva IS. Ranatunge RR, et al. Among authors: young dv. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6049-52. doi: 10.1016/j.bmcl.2004.09.073. Bioorg Med Chem Lett. 2004. PMID: 15546727

6

3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone as a potent and orally active cyclooxygenase-2 selective inhibitor: synthesis and biological evaluation.

Khanapure SP, Augustyniak ME, Earl RA, Garvey DS, Letts LG, Martino AM, Murty MG, Schwalb DJ, Shumway MJ, Trocha AM, Young DV, Zemtseva IS, Janero DR. Khanapure SP, et al. Among authors: young dv. J Med Chem. 2005 Jun 2;48(11):3930-4. doi: 10.1021/jm0582064. J Med Chem. 2005. PMID: 15916445

7

Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: nitric oxide-donor naproxen prodrugs.

Ranatunge RR, Augustyniak ME, Dhawan V, Ellis JL, Garvey DS, Janero DR, Letts LG, Richardson SK, Shumway MJ, Trocha AM, Young DV, Zemtseva IS. Ranatunge RR, et al. Among authors: young dv. Bioorg Med Chem. 2006 Apr 15;14(8):2589-99. doi: 10.1016/j.bmc.2005.11.040. Epub 2005 Dec 13. Bioorg Med Chem. 2006. PMID: 16356728

8

Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors.

Wey SJ, Augustyniak ME, Cochran ED, Ellis JL, Fang X, Garvey DS, Janero DR, Letts LG, Martino AM, Melim TL, Murty MG, Richardson SK, Schroeder JD, Selig WM, Trocha AM, Wexler RS, Young DV, Zemtseva IS, Zifcak BM. Wey SJ, et al. Among authors: young dv. J Med Chem. 2007 Dec 13;50(25):6367-82. doi: 10.1021/jm0611861. Epub 2007 Nov 10. J Med Chem. 2007. PMID: 17994684

9

Nitrosylated bovine serum albumin derivatives as pharmacologically active nitric oxide congeners.

Ewing JF, Young DV, Janero DR, Garvey DS, Grinnell TA. Ewing JF, et al. Among authors: young dv. J Pharmacol Exp Ther. 1997 Nov;283(2):947-54. J Pharmacol Exp Ther. 1997. PMID: 9353418

10

Suppression of proliferation of human coronary artery smooth muscle cells by the nitric oxide donor, S-nitrosoglutathione, is cGMP-independent.

Young DV, Serebryanik D, Janero DR, Tam SW. Young DV, et al. Mol Cell Biol Res Commun. 2000 Jul;4(1):32-6. doi: 10.1006/mcbr.2000.0254. Mol Cell Biol Res Commun. 2000. PMID: 11152625

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