Alworth WL - Search Results

1

Suicide inhibitors of cytochrome P450 1A1 and P450 2B1.

Hopkins NE, Foroozesh MK, Alworth WL. Hopkins NE, et al. Among authors: alworth wl. Biochem Pharmacol. 1992 Aug 18;44(4):787-96. doi: 10.1016/0006-2952(92)90417-h. Biochem Pharmacol. 1992. PMID: 1510726

2

Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.

Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP. Foroozesh M, et al. Among authors: alworth wl. Chem Res Toxicol. 1997 Jan;10(1):91-102. doi: 10.1021/tx960064g. Chem Res Toxicol. 1997. PMID: 9074808

3

Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.

Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP. Yun CH, et al. Among authors: alworth wl. Biochemistry. 1992 Nov 3;31(43):10556-63. doi: 10.1021/bi00158a019. Biochemistry. 1992. PMID: 1420171

4

Effects of 1-ethynylpyrene and related inhibitors of P450 isozymes upon benzo[a]pyrene metabolism by liver microsomes.

Hall M, Parker DK, Grover PL, Lu JY, Hopkins NE, Alworth WL. Hall M, et al. Among authors: alworth wl. Chem Biol Interact. 1990;76(2):181-92. doi: 10.1016/0009-2797(90)90087-4. Chem Biol Interact. 1990. PMID: 2225228

5

Mechanism-based inactivation of cytochrome P450 2B1 by 9-ethynylphenanthrene.

Roberts ES, Hopkins NE, Zaluzec EJ, Gage DA, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: alworth wl. Arch Biochem Biophys. 1995 Nov 10;323(2):295-302. doi: 10.1006/abbi.1995.9961. Arch Biochem Biophys. 1995. PMID: 7487091

6

Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.

Roberts ES, Ballou DP, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: alworth wl. Arch Biochem Biophys. 1995 Nov 10;323(2):303-12. doi: 10.1006/abbi.1995.9960. Arch Biochem Biophys. 1995. PMID: 7487092

7

Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide.

Roberts ES, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: alworth wl. Chem Res Toxicol. 1993 Jul-Aug;6(4):470-9. doi: 10.1021/tx00034a013. Chem Res Toxicol. 1993. PMID: 8374044

8

Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes.

Roberts ES, Hopkins NE, Foroozesh M, Alworth WL, Halpert JR, Hollenberg PF. Roberts ES, et al. Among authors: alworth wl. Drug Metab Dispos. 1997 Nov;25(11):1242-8. Drug Metab Dispos. 1997. PMID: 9351899 Clinical Trial.

9

Induction of CYP102 (cytochrome P450BM-3) in Bacillus megaterium by 17 beta-estradiol and 4-sec-butylphenol.

Hopkins NE, English N, Hughes V, Rowley CW, Wolf CR, Alworth WL. Hopkins NE, et al. Among authors: alworth wl. Biochem Biophys Res Commun. 1998 Mar 27;244(3):868-72. doi: 10.1006/bbrc.1998.8170. Biochem Biophys Res Commun. 1998. PMID: 9535758

10

Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP. Shimada T, et al. Among authors: alworth wl. Chem Res Toxicol. 1998 Sep;11(9):1048-56. doi: 10.1021/tx980090+. Chem Res Toxicol. 1998. PMID: 9760279

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