Augustyns K - Search Results

1

Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator.

Joossens J, Van der Veken P, Lambeir AM, Augustyns K, Haemers A. Joossens J, et al. Among authors: augustyns k. J Med Chem. 2004 May 6;47(10):2411-3. doi: 10.1021/jm0499209. J Med Chem. 2004. PMID: 15115382

2

Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV.

Lambeir AM, Borloo M, De Meester I, Belyaev A, Augustyns K, Hendriks D, Scharpé S, Haemers A. Lambeir AM, et al. Among authors: augustyns k. Biochim Biophys Acta. 1996 May 21;1290(1):76-82. doi: 10.1016/0304-4165(96)00012-8. Biochim Biophys Acta. 1996. PMID: 8645710

3

Development and evaluation of peptide-based prolyl oligopeptidase inhibitors--introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design.

Goossens F, Vanhoof G, De Meester I, Augustyns K, Borloo M, Tourwe D, Haemers A, Scharpé S. Goossens F, et al. Among authors: augustyns k. Eur J Biochem. 1997 Nov 15;250(1):177-83. doi: 10.1111/j.1432-1033.1997.00177.x. Eur J Biochem. 1997. PMID: 9432007 Free article.

4

Truncation of macrophage-derived chemokine by CD26/ dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interaction.

Proost P, Struyf S, Schols D, Opdenakker G, Sozzani S, Allavena P, Mantovani A, Augustyns K, Bal G, Haemers A, Lambeir AM, Scharpé S, Van Damme J, De Meester I. Proost P, et al. Among authors: augustyns k. J Biol Chem. 1999 Feb 12;274(7):3988-93. doi: 10.1074/jbc.274.7.3988. J Biol Chem. 1999. PMID: 9933589 Free article.

5

Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors.

Belyaev A, Zhang X, Augustyns K, Lambeir AM, De Meester I, Vedernikova I, Scharpé S, Haemers A. Belyaev A, et al. Among authors: augustyns k. J Med Chem. 1999 Mar 25;42(6):1041-52. doi: 10.1021/jm981033g. J Med Chem. 1999. PMID: 10090787

6

The unique properties of dipeptidyl-peptidase IV (DPP IV / CD26) and the therapeutic potential of DPP IV inhibitors.

Augustyns K, Bal G, Thonus G, Belyaev A, Zhang XM, Bollaert W, Lambeir AM, Durinx C, Goossens F, Haemers A. Augustyns K, et al. Curr Med Chem. 1999 Apr;6(4):311-27. Curr Med Chem. 1999. PMID: 10101215 Review.

7

Synthesis and evaluation of caffeic acid amides as antioxidants.

Rajan P, Vedernikova I, Cos P, Berghe DV, Augustyns K, Haemers A. Rajan P, et al. Among authors: augustyns k. Bioorg Med Chem Lett. 2001 Jan 22;11(2):215-7. doi: 10.1016/s0960-894x(00)00630-2. Bioorg Med Chem Lett. 2001. PMID: 11206462

8

Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family.

Lambeir AM, Proost P, Durinx C, Bal G, Senten K, Augustyns K, Scharpé S, Van Damme J, De Meester I. Lambeir AM, et al. Among authors: augustyns k. J Biol Chem. 2001 Aug 10;276(32):29839-45. doi: 10.1074/jbc.M103106200. Epub 2001 Jun 4. J Biol Chem. 2001. PMID: 11390394 Free article.

9

Trypanothione as a target in the design of antitrypanosomal and antileishmanial agents.

Augustyns K, Amssoms K, Yamani A, Rajan PK, Haemers A. Augustyns K, et al. Curr Pharm Des. 2001 Aug;7(12):1117-41. doi: 10.2174/1381612013397564. Curr Pharm Des. 2001. PMID: 11472257 Review.

10

Structural determinants for ligand binding and catalysis of triosephosphate isomerase.

Kursula I, Partanen S, Lambeir AM, Antonov DM, Augustyns K, Wierenga RK. Kursula I, et al. Among authors: augustyns k. Eur J Biochem. 2001 Oct;268(19):5189-96. doi: 10.1046/j.0014-2956.2001.02452.x. Eur J Biochem. 2001. PMID: 11589711 Free article.

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