Tsao SW - Search Results

1

The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

Qiu GH, Tan LK, Loh KS, Lim CY, Srivastava G, Tsai ST, Tsao SW, Tao Q. Qiu GH, et al. Among authors: tsao sw. Oncogene. 2004 Jun 10;23(27):4793-806. doi: 10.1038/sj.onc.1207632. Oncogene. 2004. PMID: 15122337

2

The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors.

Shu XS, Geng H, Li L, Ying J, Ma C, Wang Y, Poon FF, Wang X, Ying Y, Yeo W, Srivastava G, Tsao SW, Yu J, Sung JJ, Huang S, Chan AT, Tao Q. Shu XS, et al. Among authors: tsao sw. PLoS One. 2011;6(11):e27346. doi: 10.1371/journal.pone.0027346. Epub 2011 Nov 8. PLoS One. 2011. PMID: 22087297 Free PMC article.

3

FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma.

Shu XS, Li L, Ji M, Cheng Y, Ying J, Fan Y, Zhong L, Liu X, Tsao SW, Chan AT, Tao Q. Shu XS, et al. Among authors: tsao sw. Carcinogenesis. 2013 Sep;34(9):1984-93. doi: 10.1093/carcin/bgt165. Epub 2013 May 14. Carcinogenesis. 2013. PMID: 23677067

4

Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma.

Wong VC, Chan PL, Bernabeu C, Law S, Wang LD, Li JL, Tsao SW, Srivastava G, Lung ML. Wong VC, et al. Among authors: tsao sw. Int J Cancer. 2008 Dec 15;123(12):2816-23. doi: 10.1002/ijc.23882. Int J Cancer. 2008. PMID: 18798555

5

Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes.

Li L, Zhang Y, Fan Y, Sun K, Su X, Du Z, Tsao SW, Loh TK, Sun H, Chan AT, Zeng YX, Chan WY, Chan FK, Tao Q. Li L, et al. Among authors: tsao sw. Epigenomics. 2015;7(2):155-73. doi: 10.2217/epi.14.79. Epub 2014 Dec 5. Epigenomics. 2015. PMID: 25479246

6

Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma.

Fu L, Qin YR, Xie D, Hu L, Kwong DL, Srivastava G, Tsao SW, Guan XY. Fu L, et al. Among authors: tsao sw. Cancer Res. 2007 Nov 15;67(22):10720-6. doi: 10.1158/0008-5472.CAN-07-2411. Cancer Res. 2007. PMID: 18006814

7

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.

Chan SH, Yee Ko JM, Chan KW, Chan YP, Tao Q, Hyytiainen M, Keski-Oja J, Law S, Srivastava G, Tang J, Tsao SW, Chen H, Stanbridge EJ, Lung ML. Chan SH, et al. Among authors: tsao sw. Int J Cancer. 2011 Aug 1;129(3):565-73. doi: 10.1002/ijc.25698. Epub 2010 Nov 9. Int J Cancer. 2011. PMID: 20878956

8

Monoamine oxidase A is down-regulated in EBV-associated nasopharyngeal carcinoma.

Lee HM, Sia APE, Li L, Sathasivam HP, Chan MSA, Rajadurai P, Tsang CM, Tsao SW, Murray PG, Tao Q, Paterson IC, Yap LF. Lee HM, et al. Among authors: tsao sw. Sci Rep. 2020 Apr 9;10(1):6115. doi: 10.1038/s41598-020-63150-0. Sci Rep. 2020. PMID: 32273550 Free PMC article.

9

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype.

Wong VC, Chen H, Ko JM, Chan KW, Chan YP, Law S, Chua D, Kwong DL, Lung HL, Srivastava G, Tang JC, Tsao SW, Zabarovsky ER, Stanbridge EJ, Lung ML. Wong VC, et al. Among authors: tsao sw. Int J Cancer. 2012 Jan 1;130(1):83-95. doi: 10.1002/ijc.25970. Epub 2011 Apr 20. Int J Cancer. 2012. PMID: 21387288

10

The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-κB signaling.

Tay JK, Zhu C, Shin JH, Zhu SX, Varma S, Foley JW, Vennam S, Yip YL, Goh CK, Wang Y, Loh KS, Tsao SW, Le QT, Sunwoo JB, West RB. Tay JK, et al. Among authors: tsao sw. Sci Adv. 2022 Apr 8;8(14):eabh2445. doi: 10.1126/sciadv.abh2445. Epub 2022 Apr 8. Sci Adv. 2022. PMID: 35394843 Free PMC article.

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