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The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis.
Pan M, Liang Js JS, Fisher EA, Ginsberg HN. Pan M, et al. Among authors: fisher ea. J Biol Chem. 2002 Feb 8;277(6):4413-21. doi: 10.1074/jbc.M107460200. Epub 2001 Nov 9. J Biol Chem. 2002. PMID: 11704664 Free article.
Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants.
Jiang XC, Li Z, Liu R, Yang XP, Pan M, Lagrost L, Fisher EA, Williams KJ. Jiang XC, et al. Among authors: fisher ea. J Biol Chem. 2005 May 6;280(18):18336-40. doi: 10.1074/jbc.M500007200. Epub 2005 Feb 25. J Biol Chem. 2005. PMID: 15734742 Free article.
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
Aalto-Setälä K, Fisher EA, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan R, Ginsberg HN, Breslow JL. Aalto-Setälä K, et al. Among authors: fisher ea. J Clin Invest. 1992 Nov;90(5):1889-900. doi: 10.1172/JCI116066. J Clin Invest. 1992. PMID: 1430212 Free PMC article.
462 results