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Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase.
Ogihara T, Asano T, Katagiri H, Sakoda H, Anai M, Shojima N, Ono H, Fujishiro M, Kushiyama A, Fukushima Y, Kikuchi M, Noguchi N, Aburatani H, Gotoh Y, Komuro I, Fujita T. Ogihara T, et al. Among authors: fukushima y. Diabetologia. 2004 May;47(5):794-805. doi: 10.1007/s00125-004-1391-x. Epub 2004 May 1. Diabetologia. 2004. PMID: 15127200
Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells.
Fukushima Y, Asano T, Katagiri H, Aihara M, Saitoh T, Anai M, Funaki M, Ogihara T, Inukai K, Matsuhashi N, Oka Y, Yazaki Y, Sugano K. Fukushima Y, et al. Biochem J. 1996 Nov 15;320 ( Pt 1)(Pt 1):27-32. doi: 10.1042/bj3200027. Biochem J. 1996. PMID: 8947463 Free PMC article.
p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin.
Inukai K, Funaki M, Ogihara T, Katagiri H, Kanda A, Anai M, Fukushima Y, Hosaka T, Suzuki M, Shin BC, Takata K, Yazaki Y, Kikuchi M, Oka Y, Asano T. Inukai K, et al. Among authors: fukushima y. J Biol Chem. 1997 Mar 21;272(12):7873-82. doi: 10.1074/jbc.272.12.7873. J Biol Chem. 1997. PMID: 9065454 Free article.
1,666 results