Van Hille B - Search Results

1

Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.

Kruczynski A, Barret JM, Van Hille B, Chansard N, Astruc J, Menon Y, Duchier C, Créancier L, Hill BT. Kruczynski A, et al. Among authors: van hille b. Clin Cancer Res. 2004 May 1;10(9):3156-68. doi: 10.1158/1078-0432.ccr-1305-2. Clin Cancer Res. 2004. PMID: 15131057

2

Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for identification and characterization of topoisomerase II-targeting antitumour agents.

van Hille B, Hill BT. van Hille B, et al. Cancer Chemother Pharmacol. 1998;42(5):345-56. doi: 10.1007/s002800050828. Cancer Chemother Pharmacol. 1998. PMID: 9771947

3

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action.

Perrin D, van Hille B, Barret JM, Kruczynski A, Etiévant C, Imbert T, Hill BT. Perrin D, et al. Among authors: van hille b. Biochem Pharmacol. 2000 Apr 1;59(7):807-19. doi: 10.1016/s0006-2952(99)00382-2. Biochem Pharmacol. 2000. PMID: 10718339

4

F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.

Etiévant C, Kruczynski A, Barret JM, Perrin D, van Hille B, Guminski Y, Hill BT. Etiévant C, et al. Among authors: van hille b. Cancer Chemother Pharmacol. 2000;46(2):101-13. doi: 10.1007/s002800000133. Cancer Chemother Pharmacol. 2000. PMID: 10972479

5

Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action.

van Hille B, Etiévant C, Barret JM, Kruczynski A, Hill BT. van Hille B, et al. Anticancer Drugs. 2000 Nov;11(10):829-41. doi: 10.1097/00001813-200011000-00007. Anticancer Drugs. 2000. PMID: 11142691

6

Differential sensitivities of recombinant human topoisomerase IIalpha and beta to various classes of topoisomerase II-interacting agents.

Perrin D, van Hille B, Hill BT. Perrin D, et al. Among authors: van hille b. Biochem Pharmacol. 1998 Aug 15;56(4):503-7. doi: 10.1016/s0006-2952(98)00082-3. Biochem Pharmacol. 1998. PMID: 9763227

7

Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds.

van Hille B, Clerc X, Creighton AM, Hill BT. van Hille B, et al. Br J Cancer. 1999 Nov;81(5):800-7. doi: 10.1038/sj.bjc.6690767. Br J Cancer. 1999. PMID: 10555749 Free PMC article.

8

Differential in vitro interactions of a series of clinically useful topoisomerase-interacting compounds with the cleavage/religation activity of the human topoisomerase IIalpha and IIbeta isoforms.

van Hille B, Perrin D, Hill BT. van Hille B, et al. Anticancer Drugs. 1999 Jul;10(6):551-60. doi: 10.1097/00001813-199907000-00007. Anticancer Drugs. 1999. PMID: 10885903

9

Expression in yeast and purification of functional recombinant human poly(ADP-ribose)polymerase (PARP). Comparative pharmacological profile with that of the rat enzyme.

Perrin D, Gras S, van Hille B, Hill BT. Perrin D, et al. Among authors: van hille b. J Enzyme Inhib. 2000;15(5):461-9. doi: 10.3109/14756360009040702. J Enzyme Inhib. 2000. PMID: 11030086

10

Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

van Hille B, Richener H, Schmid P, Puettner I, Green JR, Bilbe G. van Hille B, et al. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):191-8. doi: 10.1042/bj3030191. Biochem J. 1994. PMID: 7945239 Free PMC article.

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