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The chemosensitizing activity of inhibitors of glucosylceramide synthase is mediated primarily through modulation of P-gp function.
Chai L, McLaren RP, Byrne A, Chuang WL, Huang Y, Dufault MR, Pacheco J, Madhiwalla S, Zhang X, Zhang M, Teicher BA, Carter K, Cheng SH, Leonard JP, Xiang Y, Vasconcelles M, Goldberg MA, Copeland DP, Klinger KW, Lillie J, Madden SL, Jiang YA. Chai L, et al. Among authors: huang y. Int J Oncol. 2011 Mar;38(3):701-11. doi: 10.3892/ijo.2010.888. Epub 2010 Dec 24. Int J Oncol. 2011. PMID: 21186402
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.
Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, Gladysheva TB, Teicher BA, Biemann HP, Booker M, Goldberg MA, Klinger KW, Lillie J, Madden SL, Jiang Y. Byrne A, et al. Among authors: huang y. Exp Cell Res. 2010 Jan 15;316(2):258-71. doi: 10.1016/j.yexcr.2009.08.018. Epub 2009 Sep 2. Exp Cell Res. 2010. PMID: 19732767
Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation.
Cui X, Dong Y, Zhan Q, Huang Y, Zhu Q, Zhang Z, Yang G, Wang L, Shen S, Zhao J, Lin Z, Sun J, Su Z, Xiao Y, Zhang C, Liang Y, Shen L, Ji L, Zhang X, Yin J, Wang H, Chen Z, Ju Z, Jiang C, Le R, Gao S. Cui X, et al. Among authors: huang y. Sci China Life Sci. 2024 Dec 27. doi: 10.1007/s11427-024-2754-9. Online ahead of print. Sci China Life Sci. 2024. PMID: 39754007
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