Shapiro M - Search Results

1

High throughput screening of library compounds against an oligonucleotide substructure of an RNA target.

Gooding KB, Higgs R, Hodge B, Stauffer E, Heinz B, McKnight K, Phipps K, Shapiro M, Winkler M, Ng WL, Julian RK. Gooding KB, et al. Among authors: shapiro m. J Am Soc Mass Spectrom. 2004 Jun;15(6):884-92. doi: 10.1016/j.jasms.2004.02.010. J Am Soc Mass Spectrom. 2004. PMID: 15144978 Free article.

2

Kinomics-structural biology and chemogenomics of kinase inhibitors and targets.

Vieth M, Higgs RE, Robertson DH, Shapiro M, Gragg EA, Hemmerle H. Vieth M, et al. Among authors: shapiro m. Biochim Biophys Acta. 2004 Mar 11;1697(1-2):243-57. doi: 10.1016/j.bbapap.2003.11.028. Biochim Biophys Acta. 2004. PMID: 15023365 Review.

3

RAMPED-UP NMR: multiplexed NMR-based screening for drug discovery.

Zartler ER, Hanson J, Jones BE, Kline AD, Martin G, Mo H, Shapiro MJ, Wang R, Wu H, Yan J. Zartler ER, et al. J Am Chem Soc. 2003 Sep 10;125(36):10941-6. doi: 10.1021/ja0348593. J Am Chem Soc. 2003. PMID: 12952475

4

Epitope mapping of ligand-receptor interactions by diffusion NMR.

Yan J, Kline AD, Mo H, Zartler ER, Shapiro MJ. Yan J, et al. J Am Chem Soc. 2002 Aug 28;124(34):9984-5. doi: 10.1021/ja0264347. J Am Chem Soc. 2002. PMID: 12188651

5

Complete relative stereochemistry of multiple stereocenters using only residual dipolar couplings.

Yan J, Delaglio F, Kaerner A, Kline AD, Mo H, Shapiro MJ, Smitka TA, Stephenson GA, Zartler ER. Yan J, et al. J Am Chem Soc. 2004 Apr 21;126(15):5008-17. doi: 10.1021/ja037605q. J Am Chem Soc. 2004. PMID: 15080707

6

ID NMR Methods in ligand-receptor interactions.

Zartler ER, Yan J, Mo H, Kline AD, Shapiro MJ. Zartler ER, et al. Curr Top Med Chem. 2003;3(1):25-37. doi: 10.2174/1568026033392750. Curr Top Med Chem. 2003. PMID: 12577989 Review.

7

A novel method for the determination of stereochemistry in six-membered chairlike rings using residual dipolar couplings.

Yan J, Kline AD, Mo H, Shapiro MJ, Zartler ER. Yan J, et al. J Org Chem. 2003 Mar 7;68(5):1786-95. doi: 10.1021/jo020670i. J Org Chem. 2003. PMID: 12608792

8

Design and synthesis of statine-containing BACE inhibitors.

Hu J, Cwi CL, Smiley DL, Timm D, Erickson JA, McGee JE, Yang HC, Mendel D, May PC, Shapiro M, McCarthy JR. Hu J, et al. Among authors: shapiro m. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4335-9. doi: 10.1016/j.bmcl.2003.09.037. Bioorg Med Chem Lett. 2003. PMID: 14643321

9

The absolute sign of J coupling constants determined using the order matrix calculation.

Yan J, Kline AD, Mo H, Shapiro MJ, Zartler ER. Yan J, et al. Magn Reson Chem. 2004 Nov;42(11):962-7. doi: 10.1002/mrc.1418. Magn Reson Chem. 2004. PMID: 15386557

10

Fragonomics: fragment-based drug discovery.

Zartler ER, Shapiro MJ. Zartler ER, et al. Curr Opin Chem Biol. 2005 Aug;9(4):366-70. doi: 10.1016/j.cbpa.2005.05.002. Curr Opin Chem Biol. 2005. PMID: 15925537 Review.

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