Simon MC - Search Results

1

Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.

Arsham AM, Plas DR, Thompson CB, Simon MC. Arsham AM, et al. Among authors: simon mc. Cancer Res. 2004 May 15;64(10):3500-7. doi: 10.1158/0008-5472.CAN-03-2239. Cancer Res. 2004. PMID: 15150104

2

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Maltepe E, et al. Among authors: simon mc. Nature. 1997 Mar 27;386(6623):403-7. doi: 10.1038/386403a0. Nature. 1997. PMID: 9121557

3

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription.

Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Chandel NS, et al. Among authors: simon mc. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11715-20. doi: 10.1073/pnas.95.20.11715. Proc Natl Acad Sci U S A. 1998. PMID: 9751731 Free PMC article.

4

Multilineage embryonic hematopoiesis requires hypoxic ARNT activity.

Adelman DM, Maltepe E, Simon MC. Adelman DM, et al. Among authors: simon mc. Genes Dev. 1999 Oct 1;13(19):2478-83. doi: 10.1101/gad.13.19.2478. Genes Dev. 1999. PMID: 10521392 Free PMC article.

5

The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia.

Maltepe E, Keith B, Arsham AM, Brorson JR, Simon MC. Maltepe E, et al. Among authors: simon mc. Biochem Biophys Res Commun. 2000 Jun 24;273(1):231-8. doi: 10.1006/bbrc.2000.2928. Biochem Biophys Res Commun. 2000. PMID: 10873592

6

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses.

Adelman DM, Gertsenstein M, Nagy A, Simon MC, Maltepe E. Adelman DM, et al. Among authors: simon mc. Genes Dev. 2000 Dec 15;14(24):3191-203. doi: 10.1101/gad.853700. Genes Dev. 2000. PMID: 11124810 Free PMC article.

7

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription.

Arsham AM, Plas DR, Thompson CB, Simon MC. Arsham AM, et al. Among authors: simon mc. J Biol Chem. 2002 Apr 26;277(17):15162-70. doi: 10.1074/jbc.M111162200. Epub 2002 Feb 21. J Biol Chem. 2002. PMID: 11859074 Free article.

8

Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth.

Mack FA, Rathmell WK, Arsham AM, Gnarra J, Keith B, Simon MC. Mack FA, et al. Among authors: simon mc. Cancer Cell. 2003 Jan;3(1):75-88. doi: 10.1016/s1535-6108(02)00240-4. Cancer Cell. 2003. PMID: 12559177 Free PMC article.

9

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

Arsham AM, Howell JJ, Simon MC. Arsham AM, et al. Among authors: simon mc. J Biol Chem. 2003 Aug 8;278(32):29655-60. doi: 10.1074/jbc.M212770200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777372 Free article.

10

Tumor suppression through angiogenesis inhibition.

Arsham AM, Simon MC. Arsham AM, et al. Among authors: simon mc. Methods Mol Biol. 2003;223:249-70. doi: 10.1385/1-59259-329-1:249. Methods Mol Biol. 2003. PMID: 12777736 Review. No abstract available.

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