Wright GD - Search Results

1

Cystathionine beta-lyase is important for virulence of Salmonella enterica serovar Typhimurium.

Ejim LJ, D'Costa VM, Elowe NH, Loredo-Osti JC, Malo D, Wright GD. Ejim LJ, et al. Among authors: wright gd. Infect Immun. 2004 Jun;72(6):3310-4. doi: 10.1128/IAI.72.6.3310-3314.2004. Infect Immun. 2004. PMID: 15155634 Free PMC article.

2

Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer.

Jacques SL, Ejim LJ, Wright GD. Jacques SL, et al. Among authors: wright gd. Biochim Biophys Acta. 2001 Jan 12;1544(1-2):42-54. doi: 10.1016/s0167-4838(00)00202-8. Biochim Biophys Acta. 2001. PMID: 11341915

3

Functional annotation of putative aminoglycoside antibiotic modifying proteins in Mycobacterium tuberculosis H37Rv.

Draker KA, Boehr DD, Elowe NH, Noga TJ, Wright GD. Draker KA, et al. Among authors: wright gd. J Antibiot (Tokyo). 2003 Feb;56(2):135-42. doi: 10.7164/antibiotics.56.135. J Antibiot (Tokyo). 2003. PMID: 12715873 Free article.

4

Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Jacques SL, et al. Among authors: wright gd. Chem Biol. 2003 Oct;10(10):989-95. doi: 10.1016/j.chembiol.2003.09.015. Chem Biol. 2003. PMID: 14583265

5

New phenolic inhibitors of yeast homoserine dehydrogenase.

Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. Ejim L, et al. Among authors: wright gd. Bioorg Med Chem. 2004 Jul 15;12(14):3825-30. doi: 10.1016/j.bmc.2004.05.009. Bioorg Med Chem. 2004. PMID: 15210149

6

Sampling the antibiotic resistome.

D'Costa VM, McGrann KM, Hughes DW, Wright GD. D'Costa VM, et al. Among authors: wright gd. Science. 2006 Jan 20;311(5759):374-7. doi: 10.1126/science.1120800. Science. 2006. PMID: 16424339

7

An in vitro screen of bacterial lipopolysaccharide biosynthetic enzymes identifies an inhibitor of ADP-heptose biosynthesis.

De Leon GP, Elowe NH, Koteva KP, Valvano MA, Wright GD. De Leon GP, et al. Among authors: wright gd. Chem Biol. 2006 Apr;13(4):437-41. doi: 10.1016/j.chembiol.2006.02.010. Chem Biol. 2006. PMID: 16632256

8

Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.

Ejim LJ, Blanchard JE, Koteva KP, Sumerfield R, Elowe NH, Chechetto JD, Brown ED, Junop MS, Wright GD. Ejim LJ, et al. Among authors: wright gd. J Med Chem. 2007 Feb 22;50(4):755-64. doi: 10.1021/jm061132r. J Med Chem. 2007. PMID: 17300162

9

Expanding the soil antibiotic resistome: exploring environmental diversity.

D'Costa VM, Griffiths E, Wright GD. D'Costa VM, et al. Among authors: wright gd. Curr Opin Microbiol. 2007 Oct;10(5):481-9. doi: 10.1016/j.mib.2007.08.009. Epub 2007 Oct 22. Curr Opin Microbiol. 2007. PMID: 17951101 Review.

10

Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr.

Baysarowich J, Koteva K, Hughes DW, Ejim L, Griffiths E, Zhang K, Junop M, Wright GD. Baysarowich J, et al. Among authors: wright gd. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4886-91. doi: 10.1073/pnas.0711939105. Epub 2008 Mar 18. Proc Natl Acad Sci U S A. 2008. PMID: 18349144 Free PMC article.

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