Vance JR - Search Results

1

Antitumor agents. Part 235: Novel 4'-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential.

Xiao Z, Vance JR, Bastow KF, Brossi A, Wang HK, Lee KH. Xiao Z, et al. Among authors: vance jr. Bioorg Med Chem. 2004 Jun 15;12(12):3363-9. doi: 10.1016/j.bmc.2004.03.056. Bioorg Med Chem. 2004. PMID: 15158805

2

Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.

Xiao Z, Bastow KF, Vance JR, Lee KH. Xiao Z, et al. Among authors: vance jr. Bioorg Med Chem. 2004 Jun 15;12(12):3339-44. doi: 10.1016/j.bmc.2004.03.067. Bioorg Med Chem. 2004. PMID: 15158802

3

Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.

Xiao Z, Bastow KF, Vance JR, Sidwell RS, Wang HK, Chen MS, Shi Q, Lee KH. Xiao Z, et al. Among authors: vance jr. J Med Chem. 2004 Oct 7;47(21):5140-8. doi: 10.1021/jm030609l. J Med Chem. 2004. PMID: 15456257

4

Inhibition of DNA topoisomerase II catalytic activity by the antiviral agents 7-chloro-1,3-dihydroxyacridone and 1,3,7-trihydroxyacridone.

Vance JR, Bastow KF. Vance JR, et al. Biochem Pharmacol. 1999 Aug 15;58(4):703-8. doi: 10.1016/s0006-2952(99)00140-9. Biochem Pharmacol. 1999. PMID: 10413309

5

The cytotoxicity of 2-formyl and 2-acetyl-(6-picolyl)-4N-substituted thiosemicarbazones and their copper(II) complexes.

Miller MC 3rd, Bastow KF, Stineman CN, Vance JR, Song SC, West DX, Hall IH. Miller MC 3rd, et al. Among authors: vance jr. Arch Pharm (Weinheim). 1998 Apr;331(4):121-7. doi: 10.1002/(sici)1521-4184(199804)331:4<121::aid-ardp121>3.0.co;2-t. Arch Pharm (Weinheim). 1998. PMID: 9648520

6

The cytotoxicity of copper(II) complexes of 2-acetyl-pyridyl-4N-substituted thiosemicarbazones.

Miller MC 3rd, Stineman CN, Vance JR, West DX, Hall IH. Miller MC 3rd, et al. Among authors: vance jr. Anticancer Res. 1998 Nov-Dec;18(6A):4131-9. Anticancer Res. 1998. PMID: 9891458

7

Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

Colley WC, van der Merwe M, Vance JR, Burgin AB Jr, Bjornsti MA. Colley WC, et al. Among authors: vance jr. J Biol Chem. 2004 Dec 24;279(52):54069-78. doi: 10.1074/jbc.M409764200. Epub 2004 Oct 15. J Biol Chem. 2004. PMID: 15489506 Free article.

8

Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin.

Woo MH, Vance JR, Marcos AR, Bailly C, Bjornsti MA. Woo MH, et al. Among authors: vance jr. J Biol Chem. 2002 Feb 8;277(6):3813-22. doi: 10.1074/jbc.M110484200. Epub 2001 Dec 3. J Biol Chem. 2002. PMID: 11733535 Free article.

9

Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.

Fertala J, Vance JR, Pourquier P, Pommier Y, Bjornsti MA. Fertala J, et al. Among authors: vance jr. J Biol Chem. 2000 May 19;275(20):15246-53. doi: 10.1074/jbc.275.20.15246. J Biol Chem. 2000. PMID: 10809761 Free article.

10

Studying DNA topoisomerase I-targeted drugs in the yeast. Saccharomyces cerevisiae.

Woo MH, Vance JR, Bjornsti MA. Woo MH, et al. Among authors: vance jr. Methods Mol Biol. 2001;95:303-13. doi: 10.1385/1-59259-057-8:303. Methods Mol Biol. 2001. PMID: 11089242 No abstract available.

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