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Page 1
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. Picard F, et al. Among authors: mcburney mw. Nature. 2004 Jun 17;429(6993):771-6. doi: 10.1038/nature02583. Epub 2004 Jun 2. Nature. 2004. PMID: 15175761 Free PMC article.
Mammalian SIRT1 represses forkhead transcription factors.
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. Motta MC, et al. Cell. 2004 Feb 20;116(4):551-63. doi: 10.1016/s0092-8674(04)00126-6. Cell. 2004. PMID: 14980222 Free article.
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells.
Bordone L, Motta MC, Picard F, Robinson A, Jhala US, Apfeld J, McDonagh T, Lemieux M, McBurney M, Szilvasi A, Easlon EJ, Lin SJ, Guarente L. Bordone L, et al. PLoS Biol. 2006 Feb;4(2):e31. doi: 10.1371/journal.pbio.0040031. Epub 2005 Dec 27. PLoS Biol. 2006. PMID: 16366736 Free PMC article.
Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells.
Bordone L, Motta MC, Picard F, Robinson A, Jhala US, Apfeld J, McDonagh T, Lemieux M, McBurney M, Szilvasi A, Easlon EJ, Lin SJ, Guarente L. Bordone L, et al. PLoS Biol. 2015 Dec 29;13(12):e1002346. doi: 10.1371/journal.pbio.1002346. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26714029 Free PMC article. No abstract available.
SIRT1-mediated acute cardioprotection.
Nadtochiy SM, Yao H, McBurney MW, Gu W, Guarente L, Rahman I, Brookes PS. Nadtochiy SM, et al. Among authors: mcburney mw. Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1506-12. doi: 10.1152/ajpheart.00587.2011. Epub 2011 Aug 19. Am J Physiol Heart Circ Physiol. 2011. PMID: 21856913 Free PMC article.
Dietary restriction: standing up for sirtuins.
Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E. Baur JA, et al. Science. 2010 Aug 27;329(5995):1012-3; author reply 1013-4. doi: 10.1126/science.329.5995.1012. Science. 2010. PMID: 20798296 Free PMC article. No abstract available.
SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
Yao H, Hwang JW, Sundar IK, Friedman AE, McBurney MW, Guarente L, Gu W, Kinnula VL, Rahman I. Yao H, et al. Among authors: mcburney mw. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L615-24. doi: 10.1152/ajplung.00249.2012. Epub 2013 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 24039251 Free PMC article.
SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals.
Akieda-Asai S, Zaima N, Ikegami K, Kahyo T, Yao I, Hatanaka T, Iemura S, Sugiyama R, Yokozeki T, Eishi Y, Koike M, Ikeda K, Chiba T, Yamaza H, Shimokawa I, Song SY, Matsuno A, Mizutani A, Sawabe M, Chao MV, Tanaka M, Kanaho Y, Natsume T, Sugimura H, Date Y, McBurney MW, Guarente L, Setou M. Akieda-Asai S, et al. Among authors: mcburney mw. PLoS One. 2010 Jul 23;5(7):e11755. doi: 10.1371/journal.pone.0011755. PLoS One. 2010. PMID: 20668706 Free PMC article.
173 results