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[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.
Schertl S, Hartmann RW, Batzl-Hartmann C, Bernhardt G, Spruss T, Beckenlehner K, Koch M, Krauser R, Schlemmer R, Gust R, Schönenberger H. Schertl S, et al. Among authors: spruss t. Arch Pharm (Weinheim). 2004 Jun;337(6):349-59. doi: 10.1002/ardp.200300856. Arch Pharm (Weinheim). 2004. PMID: 15188224
Establishment and Characterization of New Murine Breast Cancer Cell Lines.
Bernhardt G, Beckenlehner K, Spruss T, Schlemmer R, Reile H, Schönenberger H. Bernhardt G, et al. Among authors: spruss t. Arch Pharm (Weinheim). 2002 May;335(2):55-68. doi: 10.1002/1521-4184(200205)335:2<55::AID-ARDP55>3.0.CO;2-W. Arch Pharm (Weinheim). 2002. PMID: 12007108
Establishment and characterization of new murine breast cancer cell lines.
Bernhardt G, Beckenlehner K, Spruss T, Schlemmer R, Reile H, Schönenberger H. Bernhardt G, et al. Among authors: spruss t. Arch Pharm (Weinheim). 2002 Mar;335(2-3):55-68. doi: 10.1002/1521-4184(200203)335:2/3<55::AID-ARDP55>3.0.CO;2-Y. Arch Pharm (Weinheim). 2002. PMID: 12043456
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level.
Schertl S, Hartmann RW, Batzl-Hartmann C, Bernhardt G, Spruss T, Beckenlehner K, Koch M, Krauser R, Schlemmer R, Gust R, Schönenberger H. Schertl S, et al. Among authors: spruss t. Arch Pharm (Weinheim). 2004 Jun;337(6):335-48. doi: 10.1002/ardp.200300855. Arch Pharm (Weinheim). 2004. PMID: 15188223
Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies.
Schertl S, Hartmann RW, Batzl-Hartmann C, Spruss T, Maucher A, von Angerer E, Schiller CD, Schneider MR, Gust R, Schönenberger H. Schertl S, et al. Among authors: spruss t. J Cancer Res Clin Oncol. 2007 Mar;133(3):153-67. doi: 10.1007/s00432-006-0151-3. Epub 2006 Oct 6. J Cancer Res Clin Oncol. 2007. PMID: 17024493
[1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line.
Bernhardt G, Gust R, Reile H, vom Orde HD, Müller R, Keller C, Spruss T, Schönenberger H, Burgemeister T, Mannschreck A, et al. Bernhardt G, et al. Among authors: spruss t. J Cancer Res Clin Oncol. 1992;118(3):209-15. doi: 10.1007/BF01410136. J Cancer Res Clin Oncol. 1992. PMID: 1548286
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