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Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.
Crystal RG, Mastrangeli A, Sanders A, Cooke J, King T, Gilbert F, Henschke C, Pascal W, Herena J, Harvey BG, et al. Crystal RG, et al. Hum Gene Ther. 1995 May;6(5):667-703. doi: 10.1089/hum.1995.6.5-667. Hum Gene Ther. 1995. PMID: 7578402 No abstract available.
Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
Crystal RG, Hirschowitz E, Lieberman M, Daly J, Kazam E, Henschke C, Yankelevitz D, Kemeny N, Silverstein R, Ohwada A, Russi T, Mastrangeli A, Sanders A, Cooke J, Harvey BG. Crystal RG, et al. Hum Gene Ther. 1997 May 20;8(8):985-1001. doi: 10.1089/hum.1997.8.8-985. Hum Gene Ther. 1997. PMID: 9195221 Clinical Trial. No abstract available.
Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart.
Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK. Mack CA, et al. Among authors: crystal rg. J Thorac Cardiovasc Surg. 1998 Jan;115(1):168-76; discussion 176-7. doi: 10.1016/s0022-5223(98)70455-6. J Thorac Cardiovasc Surg. 1998. PMID: 9451061 Free PMC article.
914 results