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Beta-adrenoceptor blocker carvedilol provides cardioprotection via an adenosine-dependent mechanism in ischemic canine hearts.
Asanuma H, Minamino T, Sanada S, Takashima S, Ogita H, Ogai A, Asakura M, Liao Y, Asano Y, Shintani Y, Kim J, Shinozaki Y, Mori H, Node K, Kitamura S, Tomoike H, Hori M, Kitakaze M. Asanuma H, et al. Among authors: shinozaki y. Circulation. 2004 Jun 8;109(22):2773-9. doi: 10.1161/01.CIR.0000130917.12959.04. Epub 2004 May 17. Circulation. 2004. PMID: 15148268
Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.
Sanada S, Asanuma H, Minamino T, Node K, Takashima S, Okuda H, Shinozaki Y, Ogai A, Fujita M, Hirata A, Kim J, Asano Y, Mori H, Tomoike H, Kitamura S, Hori M, Kitakaze M. Sanada S, et al. Among authors: shinozaki y. Circulation. 2004 Oct 12;110(15):2143-9. doi: 10.1161/01.CIR.0000143830.59419.73. Epub 2004 Sep 27. Circulation. 2004. PMID: 15451788
Erythropoietin just before reperfusion reduces both lethal arrhythmias and infarct size via the phosphatidylinositol-3 kinase-dependent pathway in canine hearts.
Hirata A, Minamino T, Asanuma H, Sanada S, Fujita M, Tsukamoto O, Wakeno M, Myoishi M, Okada K, Koyama H, Komamura K, Takashima S, Shinozaki Y, Mori H, Tomoike H, Hori M, Kitakaze M. Hirata A, et al. Among authors: shinozaki y. Cardiovasc Drugs Ther. 2005 Jan;19(1):33-40. doi: 10.1007/s10557-005-6895-1. Cardiovasc Drugs Ther. 2005. PMID: 15883754
A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart.
Tsukamoto O, Asanuma H, Kim J, Minamino T, Takashima S, Ogai A, Hirata A, Fujita M, Shinozaki Y, Mori H, Tomoike H, Hori M, Kitakaze M. Tsukamoto O, et al. Among authors: shinozaki y. Biochem Biophys Res Commun. 2005 Dec 23;338(3):1460-6. doi: 10.1016/j.bbrc.2005.10.109. Epub 2005 Oct 26. Biochem Biophys Res Commun. 2005. PMID: 16271703
Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning.
Fujita M, Asanuma H, Hirata A, Wakeno M, Takahama H, Sasaki H, Kim J, Takashima S, Tsukamoto O, Minamino T, Shinozaki Y, Tomoike H, Hori M, Kitakaze M. Fujita M, et al. Among authors: shinozaki y. Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H2004-8. doi: 10.1152/ajpheart.01051.2006. Epub 2007 Jan 5. Am J Physiol Heart Circ Physiol. 2007. PMID: 17208997 Free article.
Blockade of histamine H2 receptors protects the heart against ischemia and reperfusion injury in dogs.
Asanuma H, Minamino T, Ogai A, Kim J, Asakura M, Komamura K, Sanada S, Fujita M, Hirata A, Wakeno M, Tsukamoto O, Shinozaki Y, Myoishi M, Takashima S, Tomoike H, Kitakaze M. Asanuma H, et al. Among authors: shinozaki y. J Mol Cell Cardiol. 2006 May;40(5):666-74. doi: 10.1016/j.yjmcc.2006.02.001. Epub 2006 Apr 17. J Mol Cell Cardiol. 2006. PMID: 16603184
404 results