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3-(2-aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl-uracils as orally bioavailable antagonists of the human gonadotropin releasing hormone receptor.
J Med Chem. 2004 Jul 1;47(14):3483-6. doi: 10.1021/jm049791w.
J Med Chem. 2004.
PMID: 15214774
Identification of 1-arylmethyl-3- (2-aminoethyl)-5-aryluracil as novel gonadotropin-releasing hormone receptor antagonists.
Zhu YF, Gross TD, Guo Z, Connors PJ Jr, Gao Y, Tucci FC, Struthers RS, Reinhart GJ, Saunders J, Chen TK, Killam Bonneville AL, Chen C.
Zhu YF, et al. Among authors: killam bonneville al.
J Med Chem. 2003 May 22;46(11):2023-6. doi: 10.1021/jm034041s.
J Med Chem. 2003.
PMID: 12747774
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