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Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A, Mugundu GM, Desai PB, Thummel KE, Unadkat JD. Gupta A, et al. Drug Metab Dispos. 2008 Jun;36(6):1172-80. doi: 10.1124/dmd.107.018689. Epub 2008 Mar 10. Drug Metab Dispos. 2008. PMID: 18332086
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