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The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA.
Margolis DM, Kewn S, Coull JJ, Ylisastigui L, Turner D, Wise H, Hossain MM, Lanier ER, Shaw LM, Back D. Margolis DM, et al. J Acquir Immune Defic Syndr. 2002 Sep 1;31(1):45-9. doi: 10.1097/00126334-200209010-00006. J Acquir Immune Defic Syndr. 2002. PMID: 12352149
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study.
Lehrman G, Hogue IB, Palmer S, Jennings C, Spina CA, Wiegand A, Landay AL, Coombs RW, Richman DD, Mellors JW, Coffin JM, Bosch RJ, Margolis DM. Lehrman G, et al. Among authors: margolis dm. Lancet. 2005 Aug 13-19;366(9485):549-55. doi: 10.1016/S0140-6736(05)67098-5. Lancet. 2005. PMID: 16099290 Free PMC article.
231 results