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Aldosterone directly induces myocyte apoptosis through calcineurin-dependent pathways.
Mano A, Tatsumi T, Shiraishi J, Keira N, Nomura T, Takeda M, Nishikawa S, Yamanaka S, Matoba S, Kobara M, Tanaka H, Shirayama T, Takamatsu T, Nozawa Y, Matsubara H. Mano A, et al. Among authors: tanaka h. Circulation. 2004 Jul 20;110(3):317-23. doi: 10.1161/01.CIR.0000135599.33787.CA. Epub 2004 Jul 12. Circulation. 2004. Retraction in: Circulation. 2013 Jun 11;127(23):e842. doi: 10.1161/CIR.0b013e31829bd2f4 PMID: 15249508 Retracted.
Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy.
Yamamoto T, Shirayama T, Sakatani T, Takahashi T, Tanaka H, Takamatsu T, Spitzer KW, Matsubara H. Yamamoto T, et al. Among authors: tanaka h. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1254-64. doi: 10.1152/ajpheart.00964.2006. Epub 2007 Apr 6. Am J Physiol Heart Circ Physiol. 2007. PMID: 17416604 Free article.
Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction.
Takehara N, Tsutsumi Y, Tateishi K, Ogata T, Tanaka H, Ueyama T, Takahashi T, Takamatsu T, Fukushima M, Komeda M, Yamagishi M, Yaku H, Tabata Y, Matsubara H, Oh H. Takehara N, et al. Among authors: tanaka h. J Am Coll Cardiol. 2008 Dec 2;52(23):1858-1865. doi: 10.1016/j.jacc.2008.06.052. J Am Coll Cardiol. 2008. PMID: 19038683 Free article.
p53 promotes cardiac dysfunction in diabetic mellitus caused by excessive mitochondrial respiration-mediated reactive oxygen species generation and lipid accumulation.
Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Okigaki M, Adachi S, Tanaka H, Takamatsu T, Matsubara H. Nakamura H, et al. Among authors: tanaka h. Circ Heart Fail. 2012 Jan;5(1):106-15. doi: 10.1161/CIRCHEARTFAILURE.111.961565. Epub 2011 Nov 9. Circ Heart Fail. 2012. PMID: 22075967
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