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Overexpression of nicastrin increases Abeta production.
Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Murphy MP, et al. FASEB J. 2003 Jun;17(9):1138-40. doi: 10.1096/fj.02-1050fje. Epub 2003 Apr 8. FASEB J. 2003. PMID: 12692078
Identification of a novel family of presenilin homologues.
Ponting CP, Hutton M, Nyborg A, Baker M, Jansen K, Golde TE. Ponting CP, et al. Among authors: jansen k. Hum Mol Genet. 2002 May 1;11(9):1037-44. doi: 10.1093/hmg/11.9.1037. Hum Mol Genet. 2002. PMID: 11978763
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Among authors: jansen k. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.
1,064 results