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The LKB1 tumor suppressor negatively regulates mTOR signaling.
Cancer Cell. 2004 Jul;6(1):91-9. doi: 10.1016/j.ccr.2004.06.007.
Cancer Cell. 2004.
PMID: 15261145
Free article.
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC.
Shaw RJ, et al. Among authors: kosmatka m.
Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. doi: 10.1073/pnas.0308061100. Epub 2004 Feb 25.
Proc Natl Acad Sci U S A. 2004.
PMID: 14985505
Free PMC article.
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