Iwatsubo K - Search Results

1

Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.

Iwatsubo K, Minamisawa S, Tsunematsu T, Nakagome M, Toya Y, Tomlinson JE, Umemura S, Scarborough RM, Levy DE, Ishikawa Y. Iwatsubo K, et al. J Biol Chem. 2004 Sep 24;279(39):40938-45. doi: 10.1074/jbc.M314238200. Epub 2004 Jul 15. J Biol Chem. 2004. PMID: 15262973 Free article.

2

Motor dysfunction in type 5 adenylyl cyclase-null mice.

Iwamoto T, Okumura S, Iwatsubo K, Kawabe J, Ohtsu K, Sakai I, Hashimoto Y, Izumitani A, Sango K, Ajiki K, Toya Y, Umemura S, Goshima Y, Arai N, Vatner SF, Ishikawa Y. Iwamoto T, et al. Among authors: iwatsubo k. J Biol Chem. 2003 May 9;278(19):16936-40. doi: 10.1074/jbc.C300075200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665504 Free article.

3

Isoform-specific regulation of adenylyl cyclase: a potential target in future pharmacotherapy.

Iwatsubo K, Tsunematsu T, Ishikawa Y. Iwatsubo K, et al. Expert Opin Ther Targets. 2003 Jun;7(3):441-51. doi: 10.1517/14728222.7.3.441. Expert Opin Ther Targets. 2003. PMID: 12783579 Review.

4

Disruption of type 5 adenylyl cyclase negates the developmental increase in Galphaolf expression in the striatum.

Iwamoto T, Iwatsubo K, Okumura S, Hashimoto Y, Tsunematsu T, Toya Y, Hervé D, Umemura S, Ishikawa Y. Iwamoto T, et al. Among authors: iwatsubo k. FEBS Lett. 2004 Apr 23;564(1-2):153-6. doi: 10.1016/S0014-5793(04)00333-3. FEBS Lett. 2004. PMID: 15094058 Free article.

5

Drug therapy aimed at adenylyl cyclase to regulate cyclic nucleotide signaling.

Iwatsubo K, Okumura S, Ishikawa Y. Iwatsubo K, et al. Endocr Metab Immune Disord Drug Targets. 2006 Sep;6(3):239-47. doi: 10.2174/187153006778249994. Endocr Metab Immune Disord Drug Targets. 2006. PMID: 17017975 Review.

6

Genetic manipulation and functional analysis of cAMP signalling in cardiac muscle: implications for a new target of pharmacotherapy.

Ishikawa Y, Iwatsubo K, Tsunematsu T, Okumura S. Ishikawa Y, et al. Among authors: iwatsubo k. Biochem Soc Trans. 2005 Dec;33(Pt 6):1337-40. doi: 10.1042/BST0331337. Biochem Soc Trans. 2005. PMID: 16246113

7

Characterization of beta-adrenergic receptor sequestration by newly developed whole cell binding assays.

Iwatsubo K, Tao Y, Onda T, Toya Y, Schwencke C, Fujita T, Ebina T, Iwamoto T, Hori H, Minamisawa S, Umemura S, Ishikawa Y. Iwatsubo K, et al. J Cardiovasc Pharmacol. 2003 Jan;41 Suppl 1:S53-6. J Cardiovasc Pharmacol. 2003. PMID: 12688397

8

Ischemic preconditioning prevents ischemia-induced beta-adrenergic receptor sequestration.

Iwatsubo K, Toya Y, Fujita T, Ebina T, Schwencke C, Minamisawa S, Umemura S, Ishikawa Y. Iwatsubo K, et al. J Mol Cell Cardiol. 2003 Aug;35(8):923-9. doi: 10.1016/s0022-2828(03)00173-1. J Mol Cell Cardiol. 2003. PMID: 12878479

9

Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight.

Bai Y, Tsunematsu T, Jiao Q, Ohnuki Y, Mototani Y, Shiozawa K, Jin M, Cai W, Jin HL, Fujita T, Ichikawa Y, Suita K, Kurotani R, Yokoyama U, Sato M, Iwatsubo K, Ishikawa Y, Okumura S. Bai Y, et al. Among authors: iwatsubo k. J Pharmacol Sci. 2012;119(4):381-9. doi: 10.1254/jphs.12102fp. Epub 2012 Jul 31. J Pharmacol Sci. 2012. PMID: 22850613 Free article.

10

Accumulation of molecules involved in alpha1-adrenergic signal within caveolae: caveolin expression and the development of cardiac hypertrophy.

Fujita T, Toya Y, Iwatsubo K, Onda T, Kimura K, Umemura S, Ishikawa Y. Fujita T, et al. Among authors: iwatsubo k. Cardiovasc Res. 2001 Sep;51(4):709-16. doi: 10.1016/s0008-6363(01)00348-0. Cardiovasc Res. 2001. PMID: 11530104

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