Bateman KP - Search Results

1

Discovery stage pharmacokinetics using dried blood spots.

Beaudette P, Bateman KP. Beaudette P, et al. Among authors: bateman kp. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Sep 25;809(1):153-8. doi: 10.1016/j.jchromb.2004.06.018. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15282106

2

Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography-mass spectrometry.

Bateman KP, Castonguay G, Xu L, Rowland S, Nicoll-Griffith DA, Kelly N, Chan CC. Bateman KP, et al. J Chromatogr B Biomed Sci Appl. 2001 Apr 15;754(1):245-51. doi: 10.1016/s0378-4347(00)00612-5. J Chromatogr B Biomed Sci Appl. 2001. PMID: 11318421

3

A strategy for identification of drug metabolites from dried blood spots using triple-quadrupole/linear ion trap hybrid mass spectrometry.

Mauriala T, Chauret N, Oballa R, Nicoll-Griffith DA, Bateman KP. Mauriala T, et al. Among authors: bateman kp. Rapid Commun Mass Spectrom. 2005;19(14):1984-92. doi: 10.1002/rcm.2013. Rapid Commun Mass Spectrom. 2005. PMID: 15954171

4

MSE with mass defect filtering for in vitro and in vivo metabolite identification.

Bateman KP, Castro-Perez J, Wrona M, Shockcor JP, Yu K, Oballa R, Nicoll-Griffith DA. Bateman KP, et al. Rapid Commun Mass Spectrom. 2007;21(9):1485-96. doi: 10.1002/rcm.2996. Rapid Commun Mass Spectrom. 2007. PMID: 17394128

5

Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry.

Chavez-Eng CM, Lutz RW, Li H, Goykhman D, Bateman KP, Woolf E. Chavez-Eng CM, et al. Among authors: bateman kp. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:204-14. doi: 10.1016/j.jchromb.2015.12.053. Epub 2015 Dec 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26773885

6

Detection of covalent adducts to cytochrome P450 3A4 using liquid chromatography mass spectrometry.

Bateman KP, Baker J, Wilke M, Lee J, Leriche T, Seto C, Day S, Chauret N, Ouellet M, Nicoll-Griffith DA. Bateman KP, et al. Chem Res Toxicol. 2004 Oct;17(10):1356-61. doi: 10.1021/tx0498861. Chem Res Toxicol. 2004. PMID: 15487896

7

Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).

Sturino CF, O'Neill G, Lachance N, Boyd M, Berthelette C, Labelle M, Li L, Roy B, Scheigetz J, Tsou N, Aubin Y, Bateman KP, Chauret N, Day SH, Lévesque JF, Seto C, Silva JH, Trimble LA, Carriere MC, Denis D, Greig G, Kargman S, Lamontagne S, Mathieu MC, Sawyer N, Slipetz D, Abraham WM, Jones T, McAuliffe M, Piechuta H, Nicoll-Griffith DA, Wang Z, Zamboni R, Young RN, Metters KM. Sturino CF, et al. Among authors: bateman kp. J Med Chem. 2007 Feb 22;50(4):794-806. doi: 10.1021/jm0603668. J Med Chem. 2007. PMID: 17300164

8

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.

Wu J, Hughes CS, Picard P, Letarte S, Gaudreault M, Lévesque JF, Nicoll-Griffith DA, Bateman KP. Wu J, et al. Among authors: bateman kp. Anal Chem. 2007 Jun 15;79(12):4657-65. doi: 10.1021/ac070221o. Epub 2007 May 12. Anal Chem. 2007. PMID: 17497828

9

Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studies.

Xu Y, Sun L, Anderson M, Bélanger P, Trinh V, Lavallée P, Kantesaria B, Marcoux MJ, Breidinger S, Bateman KP, Goykhman D, Woolf EJ. Xu Y, et al. Among authors: bateman kp. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:50-59. doi: 10.1016/j.jchromb.2017.08.018. Epub 2017 Aug 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28846865

10

Phosphopeptide isomer separation using capillary zone electrophoresis for the study of protein kinases and phosphatases.

Gamble TN, Ramachandran C, Bateman KP. Gamble TN, et al. Among authors: bateman kp. Anal Chem. 1999 Aug 15;71(16):3469-76. doi: 10.1021/ac990276t. Anal Chem. 1999. PMID: 10464477

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