Maciag A - Search Results

1

Mutant K-rasV12 increases COX-2, peroxides and DNA damage in lung cells.

Maciag A, Sithanandam G, Anderson LM. Maciag A, et al. Carcinogenesis. 2004 Nov;25(11):2231-7. doi: 10.1093/carcin/bgh245. Epub 2004 Jul 29. Carcinogenesis. 2004. PMID: 15284181

2

Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis.

Maciag A, Anderson LM. Maciag A, et al. Exp Lung Res. 2005 Jan-Feb;31(1):83-104. doi: 10.1080/01902140490495048. Exp Lung Res. 2005. PMID: 15765920 Free article. Review.

3

DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells.

Romanowska M, Maciag A, Smith AL, Fields JR, Fornwald LW, Kikawa KD, Kasprzak KS, Anderson LM. Romanowska M, et al. Among authors: maciag a. Free Radic Biol Med. 2007 Oct 15;43(8):1145-55. doi: 10.1016/j.freeradbiomed.2007.07.004. Epub 2007 Jul 13. Free Radic Biol Med. 2007. PMID: 17854710

4

The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.

Maciag AE, Chakrapani H, Saavedra JE, Morris NL, Holland RJ, Kosak KM, Shami PJ, Anderson LM, Keefer LK. Maciag AE, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):313-20. doi: 10.1124/jpet.110.174904. Epub 2010 Oct 20. J Pharmacol Exp Ther. 2011. PMID: 20962031 Free PMC article.

5

Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines.

Romanowska M, Kikawa KD, Fields JR, Maciag A, North SL, Shiao YH, Kasprzak KS, Anderson LM. Romanowska M, et al. Among authors: maciag a. Lung Cancer. 2007 Jan;55(1):35-42. doi: 10.1016/j.lungcan.2006.09.007. Epub 2006 Oct 18. Lung Cancer. 2007. PMID: 17052796

6

K-ras 4A and 4B mRNA levels correlate with superoxide in lung adenocarcinoma cells, while at the protein level, only mutant K-ras 4A protein correlates with superoxide.

Calvert RJ, Gupta M, Maciag A, Shiao YH, Anderson LM. Calvert RJ, et al. Among authors: maciag a. Lung Cancer. 2013 Jun;80(3):263-9. doi: 10.1016/j.lungcan.2013.01.022. Epub 2013 Mar 6. Lung Cancer. 2013. PMID: 23474128 Free PMC article.

7

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.

Maciag AE, Holland RJ, Robert Cheng YS, Rodriguez LG, Saavedra JE, Anderson LM, Keefer LK. Maciag AE, et al. Redox Biol. 2013 Feb 1;1(1):115-24. doi: 10.1016/j.redox.2012.12.002. eCollection 2013. Redox Biol. 2013. PMID: 24024144 Free PMC article.

8

Gestation stage-specific oxidative deoxyribonucleic acid damage from sidestream smoke in pregnant rats and their fetuses.

Maciag A, Bialkowska A, Espiritu I, Powell D, Alvord WG, Kasprzak KS, Anderson LM, Witschi HR. Maciag A, et al. Arch Environ Health. 2003 Apr;58(4):238-44. Arch Environ Health. 2003. PMID: 14655905

9

Nitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells.

Maciag AE, Holland RJ, Kim Y, Kumari V, Luthers CE, Sehareen WS, Biswas D, Morris NL, Ji X, Anderson LM, Saavedra JE, Keefer LK. Maciag AE, et al. J Med Chem. 2014 Mar 27;57(6):2292-302. doi: 10.1021/jm401550d. Epub 2014 Feb 25. J Med Chem. 2014. PMID: 24521039 Free PMC article.

10

Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs.

Maciag AE, Nandurdikar RS, Hong SY, Chakrapani H, Diwan B, Morris NL, Shami PJ, Shiao YH, Anderson LM, Keefer LK, Saavedra JE. Maciag AE, et al. J Med Chem. 2011 Nov 24;54(22):7751-8. doi: 10.1021/jm2004128. Epub 2011 Oct 28. J Med Chem. 2011. PMID: 22003962 Free PMC article.

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