Freyne E - Search Results

1

Cardiac and hemodynamic effects of intravenous R 80122, a new phosphodiesterase III inhibitor, in anesthetized and awake dogs.

Van de Water A, d'Aubioul J, Van Gerven W, de Chaffoy de Courcelles D, Freyne E, Xhonneux R, Reneman RS, Janssen PA. Van de Water A, et al. Among authors: freyne e. Arch Int Pharmacodyn Ther. 1992 Mar-Apr;316:60-74. Arch Int Pharmacodyn Ther. 1992. PMID: 1530374

2

Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds.

de Cheffoy de Courcelles D, de Loore K, Freyne E, Janssen PA. de Cheffoy de Courcelles D, et al. Among authors: freyne e. J Pharmacol Exp Ther. 1992 Oct;263(1):6-14. J Pharmacol Exp Ther. 1992. PMID: 1328613

3

R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade, combined in one molecule.

De Clerck F, Beetens J, de Chaffoy de Courcelles D, Vercammen E, Freyne E, Janssen PA. De Clerck F, et al. Among authors: freyne e. Prog Clin Biol Res. 1989;301:567-72. Prog Clin Biol Res. 1989. PMID: 2529556 No abstract available.

4

R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitro.

De Clerck F, Beetens J, de Chaffoy de Courcelles D, Freyne E, Janssen PA. De Clerck F, et al. Among authors: freyne e. Thromb Haemost. 1989 Feb 28;61(1):35-42. Thromb Haemost. 1989. PMID: 2546278

5

R 76713, a new specific non-steroidal aromatase inhibitor.

Wouters W, De Coster R, Krekels M, van Dun J, Beerens D, Haelterman C, Raeymaekers A, Freyne E, Van Gelder J, Venet M, et al. Wouters W, et al. Among authors: freyne e. J Steroid Biochem. 1989 Jun;32(6):781-8. doi: 10.1016/0022-4731(89)90453-6. J Steroid Biochem. 1989. PMID: 2755126

6

R 75251, a new inhibitor of steroid biosynthesis.

Bruynseels J, De Coster R, Van Rooy P, Wouters W, Coene MC, Snoeck E, Raeymaekers A, Freyne E, Sanz G, Vanden Bussche G, et al. Bruynseels J, et al. Among authors: freyne e. Prostate. 1990;16(4):345-57. doi: 10.1002/pros.2990160409. Prostate. 1990. PMID: 2164659

7

Comparative effects of the aromatase inhibitor R76713 and of its enantiomers R83839 and R83842 on steroid biosynthesis in vitro and in vivo.

Wouters W, De Coster R, van Dun J, Krekels MD, Dillen A, Raeymaekers A, Freyne E, Van Gelder J, Sanz G, Venet M, et al. Wouters W, et al. Among authors: freyne e. J Steroid Biochem Mol Biol. 1990 Dec 20;37(6):1049-54. doi: 10.1016/0960-0760(90)90464-v. J Steroid Biochem Mol Biol. 1990. PMID: 2178362

8

Identification of R146225 as a novel, orally active inhibitor of interleukin-5 biosynthesis.

Van Wauwe J, Aerts F, Cools M, Deroose F, Freyne E, Goossens J, Hermans B, Lacrampe J, Van Genechten H, Van Gerven F, Van Nyen G. Van Wauwe J, et al. Among authors: freyne e. J Pharmacol Exp Ther. 2000 Nov;295(2):655-61. J Pharmacol Exp Ther. 2000. PMID: 11046102

9

Synthesis of LIAZAL, a retinoic acid metabolism blocking agent (RAMBA) with potential clinical applications in oncology and dermatology.

Freyne E, Raeymaekers A, Venet M, Sanz G, Wouters W, De Coster R, Wauwe JV. Freyne E, et al. Bioorg Med Chem Lett. 1998 Feb 3;8(3):267-72. doi: 10.1016/s0960-894x(98)00004-3. Bioorg Med Chem Lett. 1998. PMID: 9871667

10

4-methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the farnesyltransferase inhibitor ZARNESTRA.

Angibaud P, Saha AK, Bourdrez X, End DW, Freyne E, Lezouret P, Mannens G, Mevellec L, Meyer C, Pilatte I, Poncelet V, Roux B, Smets G, Van Dun J, Venet M, Wouters W. Angibaud P, et al. Among authors: freyne e. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4361-4. doi: 10.1016/j.bmcl.2003.09.043. Bioorg Med Chem Lett. 2003. PMID: 14643326

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