Bakhtiar R - Search Results

1

Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant.

Sanchez RI, Wang RW, Newton DJ, Bakhtiar R, Lu P, Chiu SH, Evans DC, Huskey SE. Sanchez RI, et al. Among authors: bakhtiar r. Drug Metab Dispos. 2004 Nov;32(11):1287-92. doi: 10.1124/dmd.104.000216. Epub 2004 Aug 10. Drug Metab Dispos. 2004. PMID: 15304427

2

Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets.

Huskey SE, Dean BJ, Bakhtiar R, Sanchez RI, Tattersall FD, Rycroft W, Hargreaves R, Watt AP, Chicchi GG, Keohane C, Hora DF, Chiu SH. Huskey SE, et al. Among authors: bakhtiar r. Drug Metab Dispos. 2003 Jun;31(6):785-91. doi: 10.1124/dmd.31.6.785. Drug Metab Dispos. 2003. PMID: 12756213

3

Integration of knowledge-based metabolic predictions with liquid chromatography data-dependent tandem mass spectrometry for drug metabolism studies: application to studies on the biotransformation of indinavir.

Anari MR, Sanchez RI, Bakhtiar R, Franklin RB, Baillie TA. Anari MR, et al. Among authors: bakhtiar r. Anal Chem. 2004 Feb 1;76(3):823-32. doi: 10.1021/ac034980s. Anal Chem. 2004. PMID: 14750881

4

Trace level quantification of deuterated 17beta-estradiol and estrone in ovariectomized mouse plasma and brain using liquid chromatography/tandem mass spectrometry following dansylation reaction.

Xia YQ, Chang SW, Patel S, Bakhtiar R, Karanam B, Evans DC. Xia YQ, et al. Among authors: bakhtiar r. Rapid Commun Mass Spectrom. 2004;18(14):1621-8. doi: 10.1002/rcm.1530. Rapid Commun Mass Spectrom. 2004. PMID: 15282788

5

Derivatization of ethinylestradiol with dansyl chloride to enhance electrospray ionization: application in trace analysis of ethinylestradiol in rhesus monkey plasma.

Anari MR, Bakhtiar R, Zhu B, Huskey S, Franklin RB, Evans DC. Anari MR, et al. Among authors: bakhtiar r. Anal Chem. 2002 Aug 15;74(16):4136-44. doi: 10.1021/ac025712h. Anal Chem. 2002. PMID: 12199585

6

High-throughput approaches to the quantitative analysis of ketoconazole, a potent inhibitor of cytochrome P450 3A4, in human plasma.

Ramos L, Brignol N, Bakhtiar R, Ray T, Mc Mahon LM, Tse FL. Ramos L, et al. Among authors: bakhtiar r. Rapid Commun Mass Spectrom. 2000;14(23):2282-93. doi: 10.1002/1097-0231(20001215)14:23<2282::AID-RCM164>3.0.CO;2-V. Rapid Commun Mass Spectrom. 2000. PMID: 11114039

7

Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome P450s.

Anari MR, Bakhtiar R, Franklin RB, Pearson PG, Baillie TA. Anari MR, et al. Among authors: bakhtiar r. Anal Chem. 2003 Feb 1;75(3):469-78. doi: 10.1021/ac026157m. Anal Chem. 2003. PMID: 12585472

8

Identification of novel metabolites of pioglitazone in rat and dog.

Shen Z, Reed JR, Creighton M, Liu DQ, Tang YS, Hora DF, Feeney W, Szewczyk J, Bakhtiar R, Franklin RB, Vincent SH. Shen Z, et al. Among authors: bakhtiar r. Xenobiotica. 2003 May;33(5):499-509. doi: 10.1080/0049825031000085951. Xenobiotica. 2003. PMID: 12746106

9

Use of a quadrupole linear ion trap mass spectrometer in metabolite identification and bioanalysis.

Xia YQ, Miller JD, Bakhtiar R, Franklin RB, Liu DQ. Xia YQ, et al. Among authors: bakhtiar r. Rapid Commun Mass Spectrom. 2003;17(11):1137-45. doi: 10.1002/rcm.1037. Rapid Commun Mass Spectrom. 2003. PMID: 12772269

10

Simultaneous determination of MK-0767 and seven metabolites in rat urine using liquid chromatography/tandem mass spectrometry.

Shen Z, Kochansky C, Bakhtiar R, Franklin RB, Vincent SH. Shen Z, et al. Among authors: bakhtiar r. Rapid Commun Mass Spectrom. 2004;18(18):2113-20. doi: 10.1002/rcm.1597. Rapid Commun Mass Spectrom. 2004. PMID: 15317046

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