Watanabe M - Search Results

1

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.

Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J, Thomas G. Um SH, et al. Among authors: watanabe m. Nature. 2004 Sep 9;431(7005):200-5. doi: 10.1038/nature02866. Epub 2004 Aug 11. Nature. 2004. PMID: 15306821

2

Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice.

Koutnikova H, Cock TA, Watanabe M, Houten SM, Champy MF, Dierich A, Auwerx J. Koutnikova H, et al. Among authors: watanabe m. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14457-62. doi: 10.1073/pnas.2336090100. Epub 2003 Nov 5. Proc Natl Acad Sci U S A. 2003. PMID: 14603033 Free PMC article.

3

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.

Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. Tanaka T, et al. Among authors: watanabe y, watanabe m. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15924-9. doi: 10.1073/pnas.0306981100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676330 Free PMC article.

4

Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice.

Fajas L, Annicotte JS, Miard S, Sarruf D, Watanabe M, Auwerx J. Fajas L, et al. Among authors: watanabe m. J Clin Invest. 2004 May;113(9):1288-95. doi: 10.1172/JCI18555. J Clin Invest. 2004. PMID: 15124020 Free PMC article.

5

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA, Moore DD, Auwerx J. Watanabe M, et al. J Clin Invest. 2004 May;113(10):1408-18. doi: 10.1172/JCI21025. J Clin Invest. 2004. PMID: 15146238 Free PMC article.

6

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.

Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC, Auwerx J. Watanabe M, et al. Nature. 2006 Jan 26;439(7075):484-9. doi: 10.1038/nature04330. Epub 2006 Jan 8. Nature. 2006. PMID: 16400329

7

Endocrine functions of bile acids.

Houten SM, Watanabe M, Auwerx J. Houten SM, et al. Among authors: watanabe m. EMBO J. 2006 Apr 5;25(7):1419-25. doi: 10.1038/sj.emboj.7601049. Epub 2006 Mar 16. EMBO J. 2006. PMID: 16541101 Free PMC article. Review.

8

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure.

Watanabe M, Horai Y, Houten SM, Morimoto K, Sugizaki T, Arita E, Mataki C, Sato H, Tanigawara Y, Schoonjans K, Itoh H, Auwerx J. Watanabe M, et al. J Biol Chem. 2011 Jul 29;286(30):26913-20. doi: 10.1074/jbc.M111.248203. Epub 2011 Jun 1. J Biol Chem. 2011. PMID: 21632533 Free PMC article.

9

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

Harach T, Pols TW, Nomura M, Maida A, Watanabe M, Auwerx J, Schoonjans K. Harach T, et al. Among authors: watanabe m. Sci Rep. 2012;2:430. doi: 10.1038/srep00430. Epub 2012 May 30. Sci Rep. 2012. PMID: 22666533 Free PMC article.

10

Vitamin D and energy homeostasis: of mice and men.

Bouillon R, Carmeliet G, Lieben L, Watanabe M, Perino A, Auwerx J, Schoonjans K, Verstuyf A. Bouillon R, et al. Among authors: watanabe m. Nat Rev Endocrinol. 2014 Feb;10(2):79-87. doi: 10.1038/nrendo.2013.226. Epub 2013 Nov 19. Nat Rev Endocrinol. 2014. PMID: 24247221 Review.

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