Kamal A - Search Results

1

Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.

Kamal A, Ramulu P, Srinivas O, Ramesh G, Kumar PP. Kamal A, et al. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4791-4. doi: 10.1016/j.bmcl.2004.06.069. Bioorg Med Chem Lett. 2004. PMID: 15324909

2

Facile and improved synthesis of 4 beta-aminopodophyllotoxin congeners.

Kamal A, Gayatri NL, Rao NV. Kamal A, et al. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3097-100. doi: 10.1016/s0960-894x(98)00570-8. Bioorg Med Chem Lett. 1998. PMID: 9873683

3

Facile and efficient one-pot synthesis of 4beta-arylaminopodophyllotoxins: synthesis of DNA topoisomerase II inhibitors (NPF and W-68).

Kamal A, Laxman N, Ramesh G. Kamal A, et al. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2059-62. doi: 10.1016/s0960-894x(00)00407-8. Bioorg Med Chem Lett. 2000. PMID: 10999470

4

Synthesis of pyrrolo[2,1-c[1,4]benzodiazepines via reductive cyclization of omega-azido carbonyl compounds by TMSI: an efficient preparation of antibiotic DC-81 and its dimers.

Kamal A, Laxman E, Laxman N, Rao NV. Kamal A, et al. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2311-3. doi: 10.1016/s0960-894x(00)00468-6. Bioorg Med Chem Lett. 2000. PMID: 11055345

5

Solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones.

Kamal A, Reddy GS, Raghavan S. Kamal A, et al. Bioorg Med Chem Lett. 2001 Feb 12;11(3):387-9. doi: 10.1016/s0960-894x(00)00680-6. Bioorg Med Chem Lett. 2001. PMID: 11212117

6

Efficient chemoenzymatic synthesis of (S)- and (R)-5-(1-aminoethyl)-2-(cyclohexylmethoxy)benzamide: key intermediate for Src-SH2 inhibitor.

Kamal A, Sandbhor M. Kamal A, et al. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1735-8. doi: 10.1016/s0960-894x(02)00256-1. Bioorg Med Chem Lett. 2002. PMID: 12067549

7

Synthesis of C-8 alkylamino substituted pyrrolo[2,1-c][1,4]benzodiazepines as potential anti-cancer agents.

Kamal A, Laxman N, Ramesh G, Srinivas O, Ramulu P. Kamal A, et al. Bioorg Med Chem Lett. 2002 Aug 5;12(15):1917-9. doi: 10.1016/s0960-894x(02)00324-4. Bioorg Med Chem Lett. 2002. PMID: 12113808

8

Design and synthesis of C-8 linked pyrrolobenzodiazepine-naphthalimide hybrids as anti-tumour agents.

Kamal A, Reddy BS, Reddy GS, Ramesh G. Kamal A, et al. Bioorg Med Chem Lett. 2002 Aug 5;12(15):1933-5. doi: 10.1016/s0960-894x(02)00326-8. Bioorg Med Chem Lett. 2002. PMID: 12113812

9

Design, synthesis, and evaluation of new noncross-linking pyrrolobenzodiazepine dimers with efficient DNA binding ability and potent antitumor activity.

Kamal A, Ramesh G, Laxman N, Ramulu P, Srinivas O, Neelima K, Kondapi AK, Sreenu VB, Nagarajaram HA. Kamal A, et al. J Med Chem. 2002 Oct 10;45(21):4679-88. doi: 10.1021/jm020124h. J Med Chem. 2002. PMID: 12361394

10

Recent developments in the design, synthesis and structure-activity relationship studies of pyrrolo[2,1-c][1,4]benzodiazepines as DNA-interactive antitumour antibiotics.

Kamal A, Rao MV, Laxman N, Ramesh G, Reddy GS. Kamal A, et al. Curr Med Chem Anticancer Agents. 2002 Mar;2(2):215-54. doi: 10.2174/1568011023354119. Curr Med Chem Anticancer Agents. 2002. PMID: 12678745 Review.

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