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Page 1
Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.
Bikker FJ, Ligtenberg AJ, End C, Renner M, Blaich S, Lyer S, Wittig R, van't Hof W, Veerman EC, Nazmi K, de Blieck-Hogervorst JM, Kioschis P, Nieuw Amerongen AV, Poustka A, Mollenhauer J. Bikker FJ, et al. Among authors: wittig r. J Biol Chem. 2004 Nov 12;279(46):47699-703. doi: 10.1074/jbc.M406095200. Epub 2004 Sep 7. J Biol Chem. 2004. PMID: 15355985 Free article.
The scavenging capacity of DMBT1 is impaired by germline deletions.
Bikker FJ, End C, Ligtenberg AJM, Blaich S, Lyer S, Renner M, Wittig R, Nazmi K, van Nieuw Amerongen A, Poustka A, Veerman ECI, Mollenhauer J. Bikker FJ, et al. Among authors: wittig r. Immunogenetics. 2017 Jun;69(6):401-407. doi: 10.1007/s00251-017-0982-x. Epub 2017 Mar 31. Immunogenetics. 2017. PMID: 28364129 Free PMC article.
Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis.
Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlén A, Olsson J, Otto HF, O'Malley B, Poustka A. Mollenhauer J, et al. Among authors: wittig r. Genes Chromosomes Cancer. 2004 Mar;39(3):185-94. doi: 10.1002/gcc.10309. Genes Chromosomes Cancer. 2004. PMID: 14732920
DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease.
Renner M, Bergmann G, Krebs I, End C, Lyer S, Hilberg F, Helmke B, Gassler N, Autschbach F, Bikker F, Strobel-Freidekind O, Gronert-Sum S, Benner A, Blaich S, Wittig R, Hudler M, Ligtenberg AJ, Madsen J, Holmskov U, Annese V, Latiano A, Schirmacher P, Amerongen AV, D'Amato M, Kioschis P, Hafner M, Poustka A, Mollenhauer J. Renner M, et al. Among authors: wittig r. Gastroenterology. 2007 Nov;133(5):1499-509. doi: 10.1053/j.gastro.2007.08.007. Epub 2007 Aug 3. Gastroenterology. 2007. PMID: 17983803
Candidate genes for cross-resistance against DNA-damaging drugs.
Wittig R, Nessling M, Will RD, Mollenhauer J, Salowsky R, Münstermann E, Schick M, Helmbach H, Gschwendt B, Korn B, Kioschis P, Lichter P, Schadendorf D, Poustka A. Wittig R, et al. Cancer Res. 2002 Nov 15;62(22):6698-705. Cancer Res. 2002. PMID: 12438269
Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma.
Wittig-Blaich S, Wittig R, Schmidt S, Lyer S, Bewerunge-Hudler M, Gronert-Sum S, Strobel-Freidekind O, Müller C, List M, Jaskot A, Christiansen H, Hafner M, Schadendorf D, Block I, Mollenhauer J. Wittig-Blaich S, et al. Among authors: wittig r. Oncotarget. 2017 Apr 4;8(14):23760-23774. doi: 10.18632/oncotarget.15863. Oncotarget. 2017. PMID: 28423600 Free PMC article.
Thioredoxin, a regulator of gene expression.
Kontou M, Will RD, Adelfalk C, Wittig R, Poustka A, Hirsch-Kauffmann M, Schweiger M. Kontou M, et al. Among authors: wittig r. Oncogene. 2004 Mar 18;23(12):2146-52. doi: 10.1038/sj.onc.1207334. Oncogene. 2004. PMID: 14730345
263 results