Glaeser H - Search Results

1

Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans.

Glaeser H, Drescher S, Hofmann U, Heinkele G, Somogyi AA, Eichelbaum M, Fromm MF. Glaeser H, et al. Clin Pharmacol Ther. 2004 Sep;76(3):230-8. doi: 10.1016/j.clpt.2004.04.013. Clin Pharmacol Ther. 2004. PMID: 15371984

2

Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes.

Glaeser H, Drescher S, Eichelbaum M, Fromm MF. Glaeser H, et al. Br J Clin Pharmacol. 2005 Feb;59(2):199-206. doi: 10.1111/j.1365-2125.2004.02265.x. Br J Clin Pharmacol. 2005. PMID: 15676042 Free PMC article. Clinical Trial.

3

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters.

Glaeser H, Drescher S, van der Kuip H, Behrens C, Geick A, Burk O, Dent J, Somogyi A, Von Richter O, Griese EU, Eichelbaum M, Fromm MF. Glaeser H, et al. Clin Pharmacol Ther. 2002 Mar;71(3):131-40. doi: 10.1067/mcp.2002.121370. Clin Pharmacol Ther. 2002. PMID: 11907487 Clinical Trial.

4

P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.

Drescher S, Glaeser H, Mürdter T, Hitzl M, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: glaeser h. Clin Pharmacol Ther. 2003 Mar;73(3):223-31. doi: 10.1067/mcp.2003.27. Clin Pharmacol Ther. 2003. PMID: 12621387

5

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.

Becquemont L, Glaeser H, Drescher S, Hitzl M, Simon N, Murdter TE, Heinkele G, Hofmann U, Schaefer C, Burk O, Verstuyft C, Eichelbaum M, Fromm MF. Becquemont L, et al. Among authors: glaeser h. Clin Pharmacol Ther. 2006 May;79(5):449-60. doi: 10.1016/j.clpt.2006.01.005. Epub 2006 Apr 11. Clin Pharmacol Ther. 2006. PMID: 16678547 Clinical Trial.

6

Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.

Igel S, Drescher S, Mürdter T, Hofmann U, Heinkele G, Tegude H, Glaeser H, Brenner SS, Somogyi AA, Omari T, Schäfer C, Eichelbaum M, Fromm MF. Igel S, et al. Among authors: glaeser h. Clin Pharmacokinet. 2007;46(9):777-85. doi: 10.2165/00003088-200746090-00005. Clin Pharmacokinet. 2007. PMID: 17713975 Clinical Trial.

7

Interaction of innovative small molecule drugs used for cancer therapy with drug transporters.

Mandery K, Glaeser H, Fromm MF. Mandery K, et al. Among authors: glaeser h. Br J Pharmacol. 2012 Jan;165(2):345-62. doi: 10.1111/j.1476-5381.2011.01618.x. Br J Pharmacol. 2012. PMID: 21827448 Free PMC article. Review.

8

Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.

Bhardwaj RK, Glaeser H, Becquemont L, Klotz U, Gupta SK, Fromm MF. Bhardwaj RK, et al. Among authors: glaeser h. J Pharmacol Exp Ther. 2002 Aug;302(2):645-50. doi: 10.1124/jpet.102.034728. J Pharmacol Exp Ther. 2002. PMID: 12130727

9

Animal models and intestinal drug transport.

Glaeser H, Fromm MF. Glaeser H, et al. Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):347-61. doi: 10.1517/17425255.4.4.347. Expert Opin Drug Metab Toxicol. 2008. PMID: 18433341 Review.

10

Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mucosa.

Mandery K, Bujok K, Schmidt I, Wex T, Treiber G, Malfertheiner P, Rau TT, Amann KU, Brune K, Fromm MF, Glaeser H. Mandery K, et al. Among authors: glaeser h. J Pharmacol Exp Ther. 2010 Feb;332(2):345-51. doi: 10.1124/jpet.109.154518. Epub 2009 Oct 20. J Pharmacol Exp Ther. 2010. PMID: 19843975

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