Manser E - Search Results

1

Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells.

Zhu Y, Stolz DB, Guo F, Ross MA, Watkins SC, Tan BJ, Qi RZ, Manser E, Li QT, Bay BH, Teo TS, Duan W. Zhu Y, et al. Among authors: manser e. FASEB J. 2004 Nov;18(14):1722-4. doi: 10.1096/fj.04-1876fje. Epub 2004 Sep 16. FASEB J. 2004. PMID: 15375078

2

A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes.

Leung T, Manser E, Tan L, Lim L. Leung T, et al. Among authors: manser e. J Biol Chem. 1995 Dec 8;270(49):29051-4. doi: 10.1074/jbc.270.49.29051. J Biol Chem. 1995. PMID: 7493923 Free article.

We previously reported the cloning of a serine/threonine kinase, PAK (for p21 (Cdc42/Rac)-activated kinase), which binds to the Ras-related GTPases Cdc42Hs and Rac1 (Manser, E., Leung, T., Salihuddin, H., Zhao, Z-s., and Lim, L. (1994) Nature 367, 40-46). ...

We previously reported the cloning of a serine/threonine kinase, PAK (for p21 (Cdc42/Rac)-activated kinase), which binds to the Ras-related …

3

A brain serine/threonine protein kinase activated by Cdc42 and Rac1.

Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. Manser E, et al. Nature. 1994 Jan 6;367(6458):40-6. doi: 10.1038/367040a0. Nature. 1994. PMID: 8107774

4

The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family.

Koh CG, Tan EJ, Manser E, Lim L. Koh CG, et al. Among authors: manser e. Curr Biol. 2002 Feb 19;12(4):317-21. doi: 10.1016/s0960-9822(02)00652-8. Curr Biol. 2002. PMID: 11864573 Free article.

5

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures.

Harden N, Lee J, Loh HY, Ong YM, Tan I, Leung T, Manser E, Lim L. Harden N, et al. Among authors: manser e. Mol Cell Biol. 1996 May;16(5):1896-908. doi: 10.1128/MCB.16.5.1896. Mol Cell Biol. 1996. PMID: 8628256 Free PMC article.

6

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

Leung T, Chen XQ, Tan I, Manser E, Lim L. Leung T, et al. Among authors: manser e. Mol Cell Biol. 1998 Jan;18(1):130-40. doi: 10.1128/MCB.18.1.130. Mol Cell Biol. 1998. PMID: 9418861 Free PMC article.

7

Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation.

Dong JM, Leung T, Manser E, Lim L. Dong JM, et al. Among authors: manser e. Eur J Cell Biol. 2002 Apr;81(4):231-42. doi: 10.1078/0171-9335-00238. Eur J Cell Biol. 2002. PMID: 12018391

8

PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.

Wang H, Quah SY, Dong JM, Manser E, Tang JP, Zeng Q. Wang H, et al. Among authors: manser e. Cancer Res. 2007 Apr 1;67(7):2922-6. doi: 10.1158/0008-5472.CAN-06-3598. Cancer Res. 2007. PMID: 17409395

9

Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways.

Xie Y, Tan EJ, Wee S, Manser E, Lim L, Koh CG. Xie Y, et al. Among authors: manser e. J Cell Sci. 2008 Feb 15;121(Pt 4):514-21. doi: 10.1242/jcs.013557. Epub 2008 Jan 29. J Cell Sci. 2008. PMID: 18230650 Free article.

10

Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets.

Teo M, Manser E, Lim L. Teo M, et al. Among authors: manser e. J Biol Chem. 1995 Nov 3;270(44):26690-7. doi: 10.1074/jbc.270.44.26690. J Biol Chem. 1995. PMID: 7592896 Free article.

The brain-enriched p21cdc42/rac1-activated serine/threonine kinase, p65PAK, was identified and purified on the basis of overlays with [gamma-32P]GTP-Cdc42 onto SDS-fractionated proteins (Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994) Nature 3 …

The brain-enriched p21cdc42/rac1-activated serine/threonine kinase, p65PAK, was identified and purified on the basis of overlays with [gamma …

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