Stevens MF - Search Results

1

The experimental antitumor agents Phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.

Fichtner I, Monks A, Hose C, Stevens MF, Bradshaw TD. Fichtner I, et al. Among authors: stevens mf. Breast Cancer Res Treat. 2004 Sep;87(1):97-107. doi: 10.1023/B:BREA.0000041586.64371.88. Breast Cancer Res Treat. 2004. PMID: 15377855

2

Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole.

Loaiza-Pérez AI, Trapani V, Hose C, Singh SS, Trepel JB, Stevens MF, Bradshaw TD, Sausville EA. Loaiza-Pérez AI, et al. Among authors: stevens mf. Mol Pharmacol. 2002 Jan;61(1):13-9. doi: 10.1124/mol.61.1.13. Mol Pharmacol. 2002. PMID: 11752201

3

Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles.

Bradshaw TD, Bibby MC, Double JA, Fichtner I, Cooper PA, Alley MC, Donohue S, Stinson SF, Tomaszewjski JE, Sausville EA, Stevens MF. Bradshaw TD, et al. Among authors: stevens mf. Mol Cancer Ther. 2002 Feb;1(4):239-46. Mol Cancer Ther. 2002. PMID: 12467219

4

Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.

Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD. Berry JM, et al. Among authors: stevens mf. J Med Chem. 2005 Jan 27;48(2):639-44. doi: 10.1021/jm040859h. J Med Chem. 2005. PMID: 15658878

5

Elucidation of thioredoxin as a molecular target for antitumor quinols.

Bradshaw TD, Matthews CS, Cookson J, Chew EH, Shah M, Bailey K, Monks A, Harris E, Westwell AD, Wells G, Laughton CA, Stevens MF. Bradshaw TD, et al. Among authors: stevens mf. Cancer Res. 2005 May 1;65(9):3911-9. doi: 10.1158/0008-5472.CAN-04-4141. Cancer Res. 2005. PMID: 15867391

6

Mechanisms of acquired resistance to 2-(4-Amino-3-methylphenyl)benzothiazole in breast cancer cell lines.

Bradshaw TD, Stone EL, Trapani V, Leong CO, Matthews CS, te Poele R, Stevens MF. Bradshaw TD, et al. Among authors: stevens mf. Breast Cancer Res Treat. 2008 Jul;110(1):57-68. doi: 10.1007/s10549-007-9690-9. Epub 2007 Aug 3. Breast Cancer Res Treat. 2008. PMID: 17674193

7

Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells.

Chua MS, Kashiyama E, Bradshaw TD, Stinson SF, Brantley E, Sausville EA, Stevens MF. Chua MS, et al. Among authors: stevens mf. Cancer Res. 2000 Sep 15;60(18):5196-203. Cancer Res. 2000. PMID: 11016648

8

In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles.

Bradshaw TD, Chua MS, Browne HL, Trapani V, Sausville EA, Stevens MF. Bradshaw TD, et al. Among authors: stevens mf. Br J Cancer. 2002 Apr 22;86(8):1348-54. doi: 10.1038/sj.bjc.6600225. Br J Cancer. 2002. PMID: 11953897 Free PMC article.

9

Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo.

Leong CO, Gaskell M, Martin EA, Heydon RT, Farmer PB, Bibby MC, Cooper PA, Double JA, Bradshaw TD, Stevens MF. Leong CO, et al. Among authors: stevens mf. Br J Cancer. 2003 Feb 10;88(3):470-7. doi: 10.1038/sj.bjc.6600719. Br J Cancer. 2003. PMID: 12569393 Free PMC article.

10

Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.

Brantley E, Trapani V, Alley MC, Hose CD, Bradshaw TD, Stevens MF, Sausville EA, Stinson SF. Brantley E, et al. Among authors: stevens mf. Drug Metab Dispos. 2004 Dec;32(12):1392-401. doi: 10.1124/dmd.104.001057. Epub 2004 Sep 8. Drug Metab Dispos. 2004. PMID: 15355884

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