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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA. Wilhelm SM, et al. Among authors: lynch m. Cancer Res. 2004 Oct 1;64(19):7099-109. doi: 10.1158/0008-5472.CAN-04-1443. Cancer Res. 2004. PMID: 15466206
Antitumor activity of sorafenib in FLT3-driven leukemic cells.
Auclair D, Miller D, Yatsula V, Pickett W, Carter C, Chang Y, Zhang X, Wilkie D, Burd A, Shi H, Rocks S, Gedrich R, Abriola L, Vasavada H, Lynch M, Dumas J, Trail PA, Wilhelm SM. Auclair D, et al. Among authors: lynch m. Leukemia. 2007 Mar;21(3):439-45. doi: 10.1038/sj.leu.2404508. Epub 2007 Jan 4. Leukemia. 2007. PMID: 17205056
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models.
Chang YS, Adnane J, Trail PA, Levy J, Henderson A, Xue D, Bortolon E, Ichetovkin M, Chen C, McNabola A, Wilkie D, Carter CA, Taylor IC, Lynch M, Wilhelm S. Chang YS, et al. Among authors: lynch m. Cancer Chemother Pharmacol. 2007 Apr;59(5):561-74. doi: 10.1007/s00280-006-0393-4. Epub 2006 Dec 8. Cancer Chemother Pharmacol. 2007. PMID: 17160391
Assays of human postprenylation processing enzymes.
Choi YJ, Niedbala M, Lynch M, Symons M, Bollag G, North AK. Choi YJ, et al. Among authors: lynch m. Methods Enzymol. 2001;332:103-14. doi: 10.1016/s0076-6879(01)32195-x. Methods Enzymol. 2001. PMID: 11305089 No abstract available.
Fungal Planet description sheets: 1697-1780.
Crous PW, Wingfield MJ, Jurjević Ž, Balashov S, Osieck ER, Marin-Felix Y, Luangsa-Ard JJ, Mejía LC, Cappelli A, Parra LA, Lucchini G, Chen J, Moreno G, Faraoni M, Zhao RL, Weholt Ø, Borovička J, Jansen GM, Shivas RG, Tan YP, Akulov A, Alfenas AC, Alfenas RF, Altés A, Avchar R, Barreto RW, Catcheside DEA, Chi TY, Esteve-Raventós F, Fryar SC, Hanh LTM, Larsbrink J, Oberlies NH, Olsson L, Pancorbo F, Raja HA, Thanh VN, Thuy NT, Ajithkumar K, Akram W, Alvarado P, Angeletti B, Arumugam E, Khalilabad AA, Bandini D, Baroni TJ, Barreto GG, Boertmann D, Bose T, Castañeda Ruiz RF, Couceiro A, Cykowska-Marzencka B, Dai YC, Darmostuk V, da Silva SBG, Dearnaley JDW, de Azevedo Santiago ALCM, Declercq B, de Freitas LWS, De la Peña-Lastra S, Delgado G, de Lima CLF, Dhotre D, Dirks AC, Eisvand P, Erhard A, Ferro LO, García D, García-Martín A, Garrido-Benavent I, Gené J, Ghobad-Nejhad M, Gore G, Gunaseelan S, Gusmão LFP, Hammerbacher A, Hernández-Perez AT, Hernández-Restrepo M, Hofmann TA, Hubka V, Jiya N, Kaliyaperumal M, Keerthana KS, Ketabchi M, Kezo K, Knoppersen R, Kolarczyková D, Kumar TKA, Læssøe T, Langer E, Larsson E, Lodge DJ, Lynch MJ, Maciá-Vicente JG, Mahadevakumar S, Mateos A,… See abstract for full author list ➔ Crous PW, et al. Among authors: lynch mj. Fungal Syst Evol. 2024 Dec;14:325-577. doi: 10.3114/fuse.2024.14.19. Epub 2024 Dec 6. Fungal Syst Evol. 2024. PMID: 39830292 Free PMC article.
2,697 results