Xiao JJ - Search Results

1

Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.

Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Blaser BW, Freud AG, Chou J, Chen CS, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen CS, Caligiuri MA. Roychowdhury S, et al. Among authors: xiao jj. J Natl Cancer Inst. 2004 Oct 6;96(19):1447-57. doi: 10.1093/jnci/djh271. J Natl Cancer Inst. 2004. PMID: 15467034

2

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors.

Shah MH, Binkley P, Chan K, Xiao J, Arbogast D, Collamore M, Farra Y, Young D, Grever M. Shah MH, et al. Clin Cancer Res. 2006 Jul 1;12(13):3997-4003. doi: 10.1158/1078-0432.CCR-05-2689. Clin Cancer Res. 2006. PMID: 16818698 Clinical Trial.

3

Identification of thiols and glutathione conjugates of depsipeptide FK228 (FR901228), a novel histone protein deacetylase inhibitor, in the blood.

Xiao JJ, Byrd J, Marcucci G, Grever M, Chan KK. Xiao JJ, et al. Rapid Commun Mass Spectrom. 2003;17(8):757-66. doi: 10.1002/rcm.976. Rapid Commun Mass Spectrom. 2003. PMID: 12672127

4

A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

Byrd JC, Marcucci G, Parthun MR, Xiao JJ, Klisovic RB, Moran M, Lin TS, Liu S, Sklenar AR, Davis ME, Lucas DM, Fischer B, Shank R, Tejaswi SL, Binkley P, Wright J, Chan KK, Grever MR. Byrd JC, et al. Among authors: xiao jj. Blood. 2005 Feb 1;105(3):959-67. doi: 10.1182/blood-2004-05-1693. Epub 2004 Oct 5. Blood. 2005. PMID: 15466934 Free article. Clinical Trial.

5

Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.

Xiao JJ, Huang Y, Dai Z, Sadée W, Chen J, Liu S, Marcucci G, Byrd J, Covey JM, Wright J, Grever M, Chan KK. Xiao JJ, et al. J Pharmacol Exp Ther. 2005 Jul;314(1):467-75. doi: 10.1124/jpet.105.083956. Epub 2005 Apr 15. J Pharmacol Exp Ther. 2005. PMID: 15833893

6

Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.

Xiao JJ, Foraker AB, Swaan PW, Liu S, Huang Y, Dai Z, Chen J, Sadée W, Byrd J, Marcucci G, Chan KK. Xiao JJ, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):268-76. doi: 10.1124/jpet.104.072033. Epub 2005 Jan 5. J Pharmacol Exp Ther. 2005. PMID: 15634944

7

Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method.

Liu Z, Marcucci G, Byrd JC, Grever M, Xiao J, Chan KK. Liu Z, et al. Rapid Commun Mass Spectrom. 2006;20(7):1117-26. doi: 10.1002/rcm.2423. Rapid Commun Mass Spectrom. 2006. PMID: 16523529

8

Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance.

Fang L, Zhang G, Li C, Zheng X, Zhu L, Xiao JJ, Szakacs G, Nadas J, Chan KK, Wang PG, Sun D. Fang L, et al. Among authors: xiao jj. J Med Chem. 2006 Feb 9;49(3):932-41. doi: 10.1021/jm050800q. J Med Chem. 2006. PMID: 16451059

9

An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics.

Liu Z, Floss HG, Cassady JM, Xiao J, Chan KK. Liu Z, et al. J Pharm Biomed Anal. 2004 Nov 19;36(4):815-21. doi: 10.1016/j.jpba.2004.07.045. J Pharm Biomed Anal. 2004. PMID: 15533675

10

Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1.

Huang Y, Blower PE, Yang C, Barbacioru C, Dai Z, Zhang Y, Xiao JJ, Chan KK, Sadée W. Huang Y, et al. Among authors: xiao jj. Pharmacogenomics J. 2005;5(2):112-25. doi: 10.1038/sj.tpj.6500297. Pharmacogenomics J. 2005. PMID: 15668728

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