Lauffenburger DA - Search Results

1

The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface.

Lazar CS, Cresson CM, Lauffenburger DA, Gill GN. Lazar CS, et al. Among authors: lauffenburger da. Mol Biol Cell. 2004 Dec;15(12):5470-80. doi: 10.1091/mbc.e04-03-0239. Epub 2004 Oct 6. Mol Biol Cell. 2004. PMID: 15469991 Free PMC article.

2

The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor.

Wiley HS, Herbst JJ, Walsh BJ, Lauffenburger DA, Rosenfeld MG, Gill GN. Wiley HS, et al. Among authors: lauffenburger da. J Biol Chem. 1991 Jun 15;266(17):11083-94. J Biol Chem. 1991. PMID: 1645724 Free article.

3

The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode.

Dong J, Opresko LK, Chrisler W, Orr G, Quesenberry RD, Lauffenburger DA, Wiley HS. Dong J, et al. Among authors: lauffenburger da. Mol Biol Cell. 2005 Jun;16(6):2984-98. doi: 10.1091/mbc.e04-11-0994. Epub 2005 Apr 13. Mol Biol Cell. 2005. PMID: 15829568 Free PMC article.

4

Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization.

Wiley HS, Woolf MF, Opresko LK, Burke PM, Will B, Morgan JR, Lauffenburger DA. Wiley HS, et al. Among authors: lauffenburger da. J Cell Biol. 1998 Nov 30;143(5):1317-28. doi: 10.1083/jcb.143.5.1317. J Cell Biol. 1998. PMID: 9832559 Free PMC article.

5

Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence.

Kim HD, Guo TW, Wu AP, Wells A, Gertler FB, Lauffenburger DA. Kim HD, et al. Among authors: lauffenburger da. Mol Biol Cell. 2008 Oct;19(10):4249-59. doi: 10.1091/mbc.e08-05-0501. Epub 2008 Jul 16. Mol Biol Cell. 2008. PMID: 18632979 Free PMC article.

6

Autocrine epidermal growth factor signaling stimulates directionally persistent mammary epithelial cell migration.

Maheshwari G, Wiley HS, Lauffenburger DA. Maheshwari G, et al. Among authors: lauffenburger da. J Cell Biol. 2001 Dec 24;155(7):1123-8. doi: 10.1083/jcb.200109060. Epub 2001 Dec 24. J Cell Biol. 2001. PMID: 11756466 Free PMC article.

7

Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.

Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK. Kleiman LB, et al. Among authors: lauffenburger da. Mol Cell. 2011 Sep 2;43(5):723-37. doi: 10.1016/j.molcel.2011.07.014. Mol Cell. 2011. PMID: 21884975 Free PMC article.

8

Probability of autocrine ligand capture by cell-surface receptors: implications for ligand secretion measurements.

Forsten KE, Lauffenburger DA. Forsten KE, et al. Among authors: lauffenburger da. J Comput Biol. 1994 Spring;1(1):15-23. doi: 10.1089/cmb.1994.1.15. J Comput Biol. 1994. PMID: 8790450

9

Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner.

Ware MF, Wells A, Lauffenburger DA. Ware MF, et al. Among authors: lauffenburger da. J Cell Sci. 1998 Aug;111 ( Pt 16):2423-32. doi: 10.1242/jcs.111.16.2423. J Cell Sci. 1998. PMID: 9683636

10

2D protrusion but not motility predicts growth factor-induced cancer cell migration in 3D collagen.

Meyer AS, Hughes-Alford SK, Kay JE, Castillo A, Wells A, Gertler FB, Lauffenburger DA. Meyer AS, et al. Among authors: lauffenburger da. J Cell Biol. 2012 Jun 11;197(6):721-9. doi: 10.1083/jcb.201201003. Epub 2012 Jun 4. J Cell Biol. 2012. PMID: 22665521 Free PMC article.

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