Hoogsteen K - Search Results

1

Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane.

Showell GA, Baker R, Davis J, Hargreaves R, Freedman SB, Hoogsteen K, Patel S, Snow RJ. Showell GA, et al. Among authors: hoogsteen k. J Med Chem. 1992 Mar 6;35(5):911-6. doi: 10.1021/jm00083a016. J Med Chem. 1992. PMID: 1548680

2

Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist.

Gauthier JY, Jones T, Champion E, Charette L, Dehaven R, Ford-Hutchinson AW, Hoogsteen K, Lord A, Masson P, Piechuta H, et al. Gauthier JY, et al. Among authors: hoogsteen k. J Med Chem. 1990 Oct;33(10):2841-5. doi: 10.1021/jm00172a025. J Med Chem. 1990. PMID: 2170650

3

Tryptophan-derived NK1 antagonists: conformationally constrained heterocyclic bioisosteres of the ester linkage.

Lewis RT, Macleod AM, Merchant KJ, Kelleher F, Sanderson I, Herbert RH, Cascieri MA, Sadowski S, Ball RG, Hoogsteen K. Lewis RT, et al. Among authors: hoogsteen k. J Med Chem. 1995 Mar 17;38(6):923-33. doi: 10.1021/jm00006a011. J Med Chem. 1995. PMID: 7699709

4

Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.

Hutchinson JH, Charleson S, Evans JF, Falgueyret JP, Hoogsteen K, Jones TR, Kargman S, Macdonald D, McFarlane CS, Nicholson DW, et al. Hutchinson JH, et al. Among authors: hoogsteen k. J Med Chem. 1995 Oct 27;38(22):4538-47. doi: 10.1021/jm00022a020. J Med Chem. 1995. PMID: 7473582

5

Crystallization of human neutrophil elastase.

Williams HR, Lin TY, Navia MA, Springer JP, McKeever BM, Hoogsteen K, Dorn CP Jr. Williams HR, et al. Among authors: hoogsteen k. J Biol Chem. 1987 Dec 15;262(35):17178-81. J Biol Chem. 1987. PMID: 3680295 Free article.

6

Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum.

Singh SB, Ball RG, Bills GF, Cascales C, Gibbs JB, Goetz MA, Hoogsteen K, Jenkins RG, Liesch JM, Lingham RB, Silverman KC, Zink DL. Singh SB, et al. Among authors: hoogsteen k. J Org Chem. 1996 Nov 1;61(22):7727-7737. doi: 10.1021/jo961074p. J Org Chem. 1996. PMID: 11667727

7

Synthesis, assignment of absolute configuration, and receptor binding studies relevant to the neuroleptic activities of a series of chiral 3-substituted cyproheptadine atropisomers.

Randall WC, Anderson PS, Cresson EL, Hunt CA, Lyon TF, Rittle KE, Remy DC, Springer JP, Hirshfield JM, Hoogsteen K, Williams M, Risley EA, Totaro JA. Randall WC, et al. Among authors: hoogsteen k. J Med Chem. 1979 Oct;22(10):1222-30. doi: 10.1021/jm00196a014. J Med Chem. 1979. PMID: 41950 No abstract available.

8

1-(substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors of Trypanosoma cruzi in mice.

Chabala JC, Waits VB, Ikeler T, Patchett AA, Payne L, Peterson LH, Reamer RA, Hoogsteen K, Wyvratt M, Hanson WL, et al. Chabala JC, et al. Among authors: hoogsteen k. Experientia. 1991 Jan 15;47(1):51-3. doi: 10.1007/BF02041250. Experientia. 1991. PMID: 1900244

9

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.

Navia MA, McKeever BM, Springer JP, Lin TY, Williams HR, Fluder EM, Dorn CP, Hoogsteen K. Navia MA, et al. Among authors: hoogsteen k. Proc Natl Acad Sci U S A. 1989 Jan;86(1):7-11. doi: 10.1073/pnas.86.1.7. Proc Natl Acad Sci U S A. 1989. PMID: 2911584 Free PMC article.

10

Renin cleavage of a human kidney renin substrate analogous to human angiotensinogen, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH, that is human renin specific and is resistant to cathepsin D.

Poe M, Wu JK, Lin TY, Hoogsteen K, Bull HG, Slater EE. Poe M, et al. Among authors: hoogsteen k. Anal Biochem. 1984 Aug 1;140(2):459-67. doi: 10.1016/0003-2697(84)90194-5. Anal Biochem. 1984. PMID: 6385771

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