Schuetz JD - Search Results

1

Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice.

Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J, Daw N, Jenkins JJ 3rd, Gilbertson R, Germain GS, Harwood FC, Houghton PJ. Stewart CF, et al. Among authors: schuetz jd. Cancer Res. 2004 Oct 15;64(20):7491-9. doi: 10.1158/0008-5472.CAN-04-0096. Cancer Res. 2004. PMID: 15492275

2

Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro.

Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, Traxler P. Houghton PJ, et al. Among authors: schuetz jd. Cancer Res. 2004 Apr 1;64(7):2333-7. doi: 10.1158/0008-5472.can-03-3344. Cancer Res. 2004. PMID: 15059881

3

Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.

Leggas M, Panetta JC, Zhuang Y, Schuetz JD, Johnston B, Bai F, Sorrentino B, Zhou S, Houghton PJ, Stewart CF. Leggas M, et al. Among authors: schuetz jd. Cancer Res. 2006 May 1;66(9):4802-7. doi: 10.1158/0008-5472.CAN-05-2915. Cancer Res. 2006. PMID: 16651435

4

Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution.

Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Takenaka K, et al. Among authors: schuetz jd. Cancer Res. 2007 Jul 15;67(14):6965-72. doi: 10.1158/0008-5472.CAN-06-4720. Cancer Res. 2007. PMID: 17638908

5

ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.

Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. Morfouace M, et al. Among authors: schuetz jd. Cancer Res. 2015 Sep 15;75(18):3879-89. doi: 10.1158/0008-5472.CAN-15-0030. Epub 2015 Jul 21. Cancer Res. 2015. PMID: 26199091 Free PMC article.

6

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy.

Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD. Leggas M, et al. Among authors: schuetz jd. Mol Cell Biol. 2004 Sep;24(17):7612-21. doi: 10.1128/MCB.24.17.7612-7621.2004. Mol Cell Biol. 2004. PMID: 15314169 Free PMC article.

7

The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics.

Smith KH, Budhraja A, Lynch J, Roberts K, Panetta JC, Connelly JP, Turnis ME, Pruett-Miller SM, Schuetz JD, Mullighan CG, Opferman JT. Smith KH, et al. Among authors: schuetz jd. Mol Cancer Res. 2021 Apr;19(4):636-650. doi: 10.1158/1541-7786.MCR-20-0586. Epub 2020 Dec 7. Mol Cancer Res. 2021. PMID: 33288732 Free PMC article.

8

Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity.

Nagai S, Takenaka K, Nachagari D, Rose C, Domoney K, Sun D, Sparreboom A, Schuetz JD. Nagai S, et al. Among authors: schuetz jd. Cancer Res. 2011 Mar 1;71(5):1781-91. doi: 10.1158/0008-5472.CAN-10-1919. Epub 2011 Jan 18. Cancer Res. 2011. PMID: 21245102 Free PMC article.

9

Development and Validation of a Sensitive and Specific LC-MS/MS Method for IWR-1-Endo, a Wnt Signaling Inhibitor: Application to a Cerebral Microdialysis Study.

Nair S, Davis A, Campagne O, Schuetz JD, Stewart CF. Nair S, et al. Among authors: schuetz jd. Molecules. 2022 Aug 25;27(17):5448. doi: 10.3390/molecules27175448. Molecules. 2022. PMID: 36080214 Free PMC article.

10

Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis.

Furuya KN, Bradley G, Sun D, Schuetz EG, Schuetz JD. Furuya KN, et al. Among authors: schuetz jd, schuetz eg. Cancer Res. 1997 Sep 1;57(17):3708-16. Cancer Res. 1997. PMID: 9288777

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